Delirium Tremens: A Review of Clinical Studies.

Autor:	Kaye AD; Department of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA., Staser AN; Department of Medicine, Ross University School of Medicine, Miramar, USA., Mccollins TS; School of Medicine, American University of the Caribbean, Miramar, USA., Zheng J; School of Medicine, American University of the Caribbean, Miramar, USA., Berry FA; School of Medicine, American University of the Caribbean, Miramar, USA., Burroughs CR; School of Medicine, Louisiana State University Health Sciences Center, Shreveport, USA., Heisler M; Department of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA., Mouhaffel A; Department of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA., Ahmadzadeh S; Department of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA., Kaye AM; Department of Pharmacy Practice, Thomas J. Long School of Pharmacy and Health Sciences University of the Pacific, Stockton, USA., Shekoohi S; Department of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA., Varrassi G; Department of Pain Medicine, Paolo Procacci Foundation, Rome, ITA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Apr 04; Vol. 16 (4), pp. e57601. Date of Electronic Publication: 2024 Apr 04 (Print Publication: 2024).
DOI:	10.7759/cureus.57601
Abstrakt:	Delirium tremens (DT) is a severe condition resulting from alcohol withdrawal. This review highlights the challenges in diagnosing and managing DT and emphasizes the importance of early recognition and intervention to prevent complications and ensure optimal patient outcomes. The discussion of the pathophysiology of DT, focusing on the neurochemical imbalances involving the neurotransmitters gamma-aminobutyric acid and glutamate, explains how chronic alcohol dependence leads to these imbalances and contributes to the hyperexcitability seen in DT. The management of DT involves ensuring patient safety and alleviating symptoms, primarily through pharmacological approaches, such as benzodiazepines. Closely monitoring vital signs and electrolyte imbalances is necessary due to autonomic dysregulation associated with DT. The mention of the potential complexity of DT when coexisting with other conditions emphasizes the need for additional research to advance comprehension, identify predictive factors, and enhance its management. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2024, Kaye et al.)
Databáze:	MEDLINE
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