5-Fluorouracil-Related Pneumatosis Intestinalis: A Case Report and Review of the Literature.
| Autor: | Alsadhan MA; Internal Medicine, University of Utah, Salt Lake City, USA., Kringlen K; Medicine, University of Utah, Salt Lake City, USA., Singh M; Internal Medicine, University of Utah, Salt Lake City, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2024 Apr 04; Vol. 16 (4), pp. e57576. Date of Electronic Publication: 2024 Apr 04 (Print Publication: 2024). |
| DOI: | 10.7759/cureus.57576 |
| Abstrakt: | Pneumatosis intestinalis (PI) refers to the presence of air within the bowel wall. It can be associated with many causes including chemotherapy. We report a case of a 70-year-old male with metastatic tongue squamous cell carcinoma (SCC), whose hospital course was complicated by diarrhea and the development of PI, which was attributed to 5-fluorouracil (5-FU) chemotherapy after a comprehensive diagnostic workup and reassuring physical examination. The patient was treated conservatively with antibiotics and a bowel rest. A repeat imaging done before discharge showed stable findings. The patient was discharged afterward without complications. We highlight the importance of recognizing 5-FU as a cause for PI among patients with reassuring physical examination and diagnostic workup. Furthermore, we highlight that it may still be successfully managed with conservative measures. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2024, Alsadhan et al.) |
| Databáze: | MEDLINE |
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