Navigating the complexity of skull base osteomyelitis: a case study and comprehensive review.

Autor: Horache K; Neuroradiology Department, Specialty Hospital of Rabat, Rue Lamfadel Cherkaoui Rabat - Institut B.P 6527, Morocco., Jidal M; Neuroradiology Department, Specialty Hospital of Rabat, Rue Lamfadel Cherkaoui Rabat - Institut B.P 6527, Morocco., Kettani NE; Neuroradiology Department, Specialty Hospital of Rabat, Rue Lamfadel Cherkaoui Rabat - Institut B.P 6527, Morocco., Fikri M; Neuroradiology Department, Specialty Hospital of Rabat, Rue Lamfadel Cherkaoui Rabat - Institut B.P 6527, Morocco., Jiddane M; Neuroradiology Department, Specialty Hospital of Rabat, Rue Lamfadel Cherkaoui Rabat - Institut B.P 6527, Morocco., Touarsa F; Neuroradiology Department, Specialty Hospital of Rabat, Rue Lamfadel Cherkaoui Rabat - Institut B.P 6527, Morocco.
Jazyk: angličtina
Zdroj: Journal of surgical case reports [J Surg Case Rep] 2024 May 02; Vol. 2024 (5), pp. rjae282. Date of Electronic Publication: 2024 May 02 (Print Publication: 2024).
DOI: 10.1093/jscr/rjae282
Abstrakt: Skull base osteomyelitis is a rare and life-threatening infection of the skull base, commonly seen in elderly diabetic patients as a result of otogenic or paranasal infection. The diagnosis is based on a series of arguments, including a high clinical suspicion, imaging findings, negative biopsies for malignancy, and microbiological isolation. Complications, including abscess formation and vascular involvement, mandate a multidisciplinary treatment approach, primarily involving broad-spectrum antibiotics and surgical debridement, but the prognosis is usually poor. Herein, we describe the case of a 55-year-old male, who 15 years prior, underwent radiation therapy for nasopharyngeal carcinoma. He presented with an infection of the skull base with extensive bone erosion accompanied by an uncommon complication; an intra clival abscess. Despite aggressive antibiotic therapy, the patient ultimately succumbed to septic shock.
Competing Interests: None declared.
(Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2024.)
Databáze: MEDLINE
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