The Diversity and Evolution of Chiral Brønsted Acid Structures.

Autor: Handjaya JP; Department of Chemistry, University of British Columbia, Vancouver, British Columbia, V6T 1Z1, Canada., Patankar N; Department of Chemistry, University of British Columbia, Vancouver, British Columbia, V6T 1Z1, Canada., Reid JP; Department of Chemistry, University of British Columbia, Vancouver, British Columbia, V6T 1Z1, Canada.
Jazyk: angličtina
Zdroj: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2024 Aug 19; Vol. 30 (46), pp. e202400921. Date of Electronic Publication: 2024 Jul 31.
DOI: 10.1002/chem.202400921
Abstrakt: The chemical space of chiral Brønsted acid catalysts is defined by quantity and complexity, reflecting the diverse synthetic challenges confronted and the innovative molecular designs introduced. Here, we detail how this successful outcome is a powerful demonstration of the benefits of utilizing both local structure searches and a comprehensive understanding of catalyst performance for effective and efficient exploration of Brønsted acid properties. In this concept article we provide an evolutionary overview of this field by summarizing the approaches to catalyst optimization, the resulting structures, and functions.
(© 2024 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH.)
Databáze: MEDLINE
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