Environmental implications and nanotechnological advances in octocrylene-enriched sunscreen formulations: A comprehensive review.

Autor: Gholap AD; St. John Institute of Pharmacy and Research, Palghar, 401404, Maharashtra, India; Department of Pharmaceutics, Amrutvahini College of Pharmacy, Sangamner, 422608, Maharashtra, India., Pardeshi SR; St. John Institute of Pharmacy and Research, Palghar, 401404, Maharashtra, India., Hatvate NT; Institute of Chemical Technology, Marathwada Campus, Jalna, Maharashtra, 431203, India., Dhorkule N; St. John Institute of Pharmacy and Research, Palghar, 401404, Maharashtra, India., Sayyad SF; Department of Pharmaceutics, Amrutvahini College of Pharmacy, Sangamner, 422608, Maharashtra, India. Electronic address: sadiksayyad@gmail.com., Faiyazuddin M; School of Pharmacy, Al-Karim University, Katihar, Bihar, 854106, India; Centre for Global Health Research, Saveetha Institute of Medical and Technical Sciences, Tamil Nadu, India. Electronic address: md.faiyazuddin@gmail.com., Khalid M; Sunway Centre for Electrochemical Energy and Sustainable Technology (SCEEST), School of Engineering and Technology, Sunway University, No. 5, Jalan University, Bandar Sunway, 47500, Petaling Jaya, Selangor, Malaysia; Centre of Research Impact and Outcome, Chitkara University, Punjab, 140401 India; Chitkara Centre for Research and Development, Chitkara University, Himachal Pradesh 174103, India. Electronic address: khalids@sunway.edu.my.
Jazyk: angličtina
Zdroj: Chemosphere [Chemosphere] 2024 Jun; Vol. 358, pp. 142235. Date of Electronic Publication: 2024 May 03.
DOI: 10.1016/j.chemosphere.2024.142235
Abstrakt: Ultraviolet (UV) radiation is a major contributor to skin aging, cancer, and other detrimental health effects. Sunscreens containing FDA-approved UV filters, like avobenzone, offer protection but suffer from photodegradation and potential phototoxicity. Encapsulation, antioxidants, and photostabilizers are strategies employed to combat these drawbacks. Octocrylene, an organic UV filter, utilizes nanotechnology to enhance sun protection factor (SPF). This review examines recent literature on octocrylene-enriched sunscreens, exploring the interplay between environmental impact, nanotechnological advancements, and clinical trial insights. A critical focus is placed on the environmental consequences of sunscreen use, particularly the potential hazards UV filters pose to marine ecosystems. Research in the Mediterranean Sea suggests bacterial sensitivity to these filters, raising concerns about their integration into the food chain. This review aims to guide researchers in developing effective strategies for photostabilization of UV filters. By combining encapsulation, photostabilizers, and antioxidants, researchers can potentially reduce phototoxic effects and contribute to developing more environmentally friendly sunscreens.
Competing Interests: Declaration of competing interest The authors declare no conflicting interest regarding the publication of this manuscript. This statement is to certify that all authors have seen and approved the manuscript being submitted. On behalf of all Co-Authors, the corresponding author(s) shall bear full responsibility for the submission.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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