Paracetamol overdose in Danish children and adolescents during the Covid-19 restrictions.

Autor:	Kempf ON; Department of Paediatrics and Adolescent Medicine, Copenhagen University Hospital - Rigshospitalet., Helt TW; Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital - Rigshospitalet., Johansen KB; Department of Paediatrics and Adolescent Medicine, Aarhus University Hospital.; Department of Emergency Medicine, Horsens Regional Hospital., Rittig C; Department of Emergency Medicine, Horsens Regional Hospital., Lundby-Christensen L; Department of Paediatrics and Adolescent Medicine, Slagelse Hospital., Frederiksen MS; Department of Paediatrics and Adolescent Medicine, Copenhagen University Hospital - Herlev Hospital., Mathiesen P; Department of Paediatrics and Adolescent Medicine, Copenhagen University Hospital - Herlev Hospital., Boas M; Department of Paediatrics and Adolescent Medicine, Zealand University Hospital, Roskilde., Nielsen PB; Department of Paediatrics and Adolescent Medicine, University Hospital of Southern Denmark - Sønderjylland., Ellermann A; Department of Paediatrics and Adolescent Medicine, Holbaek Hospital., Børch K; Department of Paediatrics and Adolescence Medicine, Copenhagen University Hospital - Hvidovre Hospital., Petersen JJ; Department of Paediatrics and Adolescent Medicine, University Hospital of Southern Denmark - South-West Jutland., Petersen TH; Department of Paediatrics and Adolescent Medicine, University Hospital of Southern Denmark - Lillebaelt., Sønderskov CT; Department of Gynaecology, Obstetrics and Paediatrics, Nykøbing Falster Hospital., Andersen J; Department of Paediatrics and Adolescent Medicine, Copenhagen University hospital - North Zealand Hospital., Nielsen RG; Hans Christian Andersen Children's Hospital, Odense University Hospital, Denmark., Jeppesen EM; Department of Paediatrics and Adolescent Medicine, Copenhagen University Hospital - Rigshospitalet., Christensen VB; Department of Paediatrics and Adolescent Medicine, Copenhagen University Hospital - Rigshospitalet.
Jazyk:	angličtina
Zdroj:	Danish medical journal [Dan Med J] 2024 Apr 16; Vol. 71 (5). Date of Electronic Publication: 2024 Apr 16.
DOI:	10.61409/A08230494
Abstrakt:	Introduction: To assess the effect of long-term isolation on the mental state of Danish youth. This study aimed to investigate trends in paracetamol overdoses among people under 18 years of age in Denmark during Covid-19 restrictions as an indicator of mental health. Methods: All patients under the age of 18 years presenting with paracetamol overdose at one of the 18 paediatric departments in Denmark from 2016 to 2021 were included. They were identified in all Danish hospital databases using specific diagnostic codes. Results: From 2016 to 2021, a total of 3,217 people under 18 years of age were admitted for paracetamol overdose. Among these, 86% (n = 2,755) were girls and 14% (n = 462) were boys. During 2020, a slight (7%) decrease in admissions was observed among both boys and girls compared with the preceding four-year mean value. In 2021, the number of overdoses among girls exceeded by 35% the former all-time high from 2016. Furthermore, the number of overdoses among girls exceeded the pre-four-year period mean value by 43%. Among boys, an 8% increase was seen from the highest ever previous value recorded in 2019 and a 23% increase compared with the previous four-year mean value. Conclusions: During the first year of restrictions, a slight decrease in paracetamol overdoses was observed, possibly associated with limited accessibility. The second year showed a considerable increase in paracetamol overdoses, which may imply an affected mental state among youth during the prolonged lockdown restrictions as seen in previous epidemics. Therefore, further studies are warranted to develop a pandemic preparedness plan to protect general mental health. Funding: None. Trial Registration: Not relevant. (Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.)
Databáze:	MEDLINE
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