Long-term follow-up results of facial nerve schwannoma with good facial nerve function: a multicenter study.

Autor: Cho YS; Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.; Korean Facial Nerve Study Group, Seoul, Republic of Korea., Lee JD; Department of Otorhinolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.; Korean Facial Nerve Study Group, Seoul, Republic of Korea., Cho YS; Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.; Korean Facial Nerve Study Group, Seoul, Republic of Korea., Lee JH; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea.; Korean Facial Nerve Study Group, Seoul, Republic of Korea., Seo HW; Department of Otorhinolaryngology-Head and Neck Surgery, Hanyang University Guri Hospital, Hanyang University School of Medicine, Seoul, Republic of Korea.; Korean Facial Nerve Study Group, Seoul, Republic of Korea., Gwak JW; Department of Otorhinolaryngology-Head & Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.; Korean Facial Nerve Study Group, Seoul, Republic of Korea., Moon IS; Department of Otorhinolaryngology-Head and Neck Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea.; Korean Facial Nerve Study Group, Seoul, Republic of Korea., Choi JW; Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University School of Medicine, Daejeon, Republic of Korea.; Korean Facial Nerve Study Group, Seoul, Republic of Korea., Han GC; Department of Otorhinolaryngology-Head and Neck Surgery, Gil Hospital, Gachon University, Incheon, Republic of Korea.; Korean Facial Nerve Study Group, Seoul, Republic of Korea., Koo JW; Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seongnam-Si, Republic of Korea. jwkoo99@snu.ac.kr.; Korean Facial Nerve Study Group, Seoul, Republic of Korea. jwkoo99@snu.ac.kr., Chung JW; Department of Otorhinolaryngology-Head & Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. jwchung@amc.seoul.kr.; Korean Facial Nerve Study Group, Seoul, Republic of Korea. jwchung@amc.seoul.kr.
Jazyk: angličtina
Zdroj: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery [Eur Arch Otorhinolaryngol] 2024 Sep; Vol. 281 (9), pp. 4719-4725. Date of Electronic Publication: 2024 May 03.
DOI: 10.1007/s00405-024-08693-y
Abstrakt: Purpose: Facial nerve schwannomas (FNSs) are rare intracranial tumors, and the optimal management of these tumors remains unclear. We investigated the long-term follow-up results of FNS with good facial nerve function.
Methods: At nine medical centers in the Korean Facial Nerve Study Group, 43 patients undergoing observation periods longer than 12 months for FNS with good facial nerve function (House-Brackmann grade ≤ II) were enrolled, and clinical and radiographic data were obtained for these cases.
Results: The mean follow-up period was 63 months. In the majority of cases, tumors involved multiple segments (81.4%) and only eight cases were confined to a single site. There were no cases where the tumor was confined to the extratemporal region. Tumor size increased slightly, with an average estimated change of 0.48 mm/year. Twenty (46.5%) of 43 patients showed no change in tumor size. Seven patients (16.3%) showed worsening House-Brackmann (H-B) grade, of which two patients deteriorated from H-B grade I to II, four worsened to grade III, and one deteriorated to grade IV. The remaining 36 patients (83.7%) showed no change in facial nerve function. There was no difference in H-B grade according to tumor size at the time of diagnosis or change in tumor size.
Conclusion: We conducted a large-scale observational study of FNS with good facial nerve function. Our study showed that many patients maintained facial nerve function during long-term follow-up. Conservative management with regular examination and imaging can be an appropriate option for managing FNS with good facial nerve function.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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