LGI1-antibody encephalitis: how to approach this highly treatable dementia mimic in memory and mental health services.

Autor: Binks SNM; Oxford Autoimmune Neurology Group, Nuffield Department of Clinical Neurosciences, University of Oxford, UK.; Department of Neurology, John Radcliffe Hospital, Oxford University Hospital NHS Foundation Trust, Oxford, UK., Al-Diwani A; University Department of Psychiatry, University of Oxford, UK.; Department of Psychological Medicine, John Radcliffe Hospital, Oxford University Hospital NHS Foundation Trust, Oxford, UK.; Oxford Community Psychological Medicine Service, Oxford Health NHS Foundation Trust, Oxford, UK., Handel AE; Oxford Autoimmune Neurology Group, Nuffield Department of Clinical Neurosciences, University of Oxford, UK.; Department of Neurology, John Radcliffe Hospital, Oxford University Hospital NHS Foundation Trust, Oxford, UK.; Department of Psychological Medicine, John Radcliffe Hospital, Oxford University Hospital NHS Foundation Trust, Oxford, UK.; Oxford Community Psychological Medicine Service, Oxford Health NHS Foundation Trust, Oxford, UK., Bajorek T; Department of Psychological Medicine, John Radcliffe Hospital, Oxford University Hospital NHS Foundation Trust, Oxford, UK., Manohar S; Department of Neurology, John Radcliffe Hospital, Oxford University Hospital NHS Foundation Trust, Oxford, UK.; Department of Experimental Psychology, University of Oxford, UK.; Nuffield Department of Clinical Neurosciences, University of Oxford, UK., Husain M; Department of Neurology, John Radcliffe Hospital, Oxford University Hospital NHS Foundation Trust, Oxford, UK.; Department of Experimental Psychology, University of Oxford, UK.; Nuffield Department of Clinical Neurosciences, University of Oxford, UK., Irani SR; Oxford Autoimmune Neurology Group, Nuffield Department of Clinical Neurosciences, University of Oxford, UK.; Department of Neurology, John Radcliffe Hospital, Oxford University Hospital NHS Foundation Trust, Oxford, UK., Koychev I; University Department of Psychiatry, University of Oxford, UK; and Department of Psychological Medicine, John Radcliffe Hospital, Oxford University Hospital NHS Foundation Trust, Oxford, UK.
Jazyk: angličtina
Zdroj: The British journal of psychiatry : the journal of mental science [Br J Psychiatry] 2024 Jun; Vol. 224 (6), pp. 252-257.
DOI: 10.1192/bjp.2024.72
Abstrakt: Leucine-rich glioma-inactivated 1-antibody-encephalitis is a treatable and potentially reversible cause of cognitive and psychiatric presentations, and may mimic cognitive decline, rapidly progressive dementia and complex psychosis in older patients. This aetiology is of immediate relevance given the alternative treatment pathway required, compared with other conditions presenting with cognitive deficits.
Databáze: MEDLINE