The Effect of Liposomes of Various Compositions on the Skin and Its Derivatives After II-IIIA Degree Thermal Burns.
| Autor: | Pashkevich NI; Vitebsk State Order of Peoples' Friendship Medical University, Vitebsk, 210009 Republic of Belarus., Vilyanen DV; Institute of Basic Biological Problems, Russian Academy of Sciences, Pushchino, Moscow Region, 142290 Russian Federation., Marcinkevich AF; Vitebsk State Order of Peoples' Friendship Medical University, Vitebsk, 210009 Republic of Belarus., Borisova-Mubarakshina MM; Institute of Basic Biological Problems, Russian Academy of Sciences, Pushchino, Moscow Region, 142290 Russian Federation., Osochuk SS; Vitebsk State Order of Peoples' Friendship Medical University, Vitebsk, 210009 Republic of Belarus. |
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| Jazyk: | angličtina |
| Zdroj: | Acta naturae [Acta Naturae] 2024 Jan-Mar; Vol. 16 (1), pp. 67-76. |
| DOI: | 10.32607/actanaturae.27329 |
| Abstrakt: | This study examines the pathological processes and conditions arising from an experimental modeling of II-IIIA degree thermal burns in laboratory animals. These conditions are characterized by skin structure defects, diminished skin functions, especially the barrier function, and damage to skin derivatives like hair follicles and sebaceous glands. We compared the effect of liposomes composed of soybean lecithin of 90% phosphatidylcholine content and liposomes composed of lecithin of 26% phosphatidylcholine content on the epidermis, dermis and its capillaries, hair follicles, and the sebaceous glands of the laboratory animals 24 h after experimental modeling of II-IIIA degree thermal skin burns. We discuss the dependency of liposome effects on the skin and its derivatives on the fatty acid composition of the lecithin used, with particular focus on phosphatidylinositol, phosphatidic acids, as well as oleic and linoleic acids. (Copyright ® 2024 National Research University Higher School of Economics.) |
| Databáze: | MEDLINE |
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