Changes in the structural and functional state of the thyroid gland of small mammals when exposed to low-intensity chronic radiation.

Autor: Еrmakova O; Institute of Biology Federal Research Centre Komi Science Centre of the Ural Branch of the Russian Academy of Sciences, Kommunisticheskaya 28, Syktyvkar, Russian Federation, 167982., Raskosha О; Institute of Biology Federal Research Centre Komi Science Centre of the Ural Branch of the Russian Academy of Sciences, Kommunisticheskaya 28, Syktyvkar, Russian Federation, 167982. raskosha@ib.komisc.ru.
Jazyk: angličtina
Zdroj: Environmental science and pollution research international [Environ Sci Pollut Res Int] 2024 May; Vol. 31 (23), pp. 34170-34183. Date of Electronic Publication: 2024 May 02.
DOI: 10.1007/s11356-024-33504-6
Abstrakt: The study gives a morphofunctional assessment of the state of the thyroid gland of tundra voles (Microtus oeconomus Pall.) in conditions of an increased radiation background (the Ukhta district of the Komi Republic (Russia) and the 30-km zone of the Chernobyl NPP), as well as in an experiment with chronic external gamma irradiation in the low dose range. The work summarizes the experience of more than 35 years of field and laboratory research. The authors have noted the high sensitivity of the thyroid gland to chronic radiation against the general irradiation of the organism both in natural conditions and in the experiment. The repeatability of the observed effects in voles from natural populations and the comparability of some effects with the morphological changes occurring in animals after exposure to ionizing radiation in the experiment indicates the radiation nature of these effects. The tundra voles living in conditions of increased radiation background have been identified for a greater variety of morphological rearrangements in the thyroid parenchyma than the experimental animals. The complex and ambiguous nature of the thyroid gland responses to radiation exposure indicates the possibility of a significant increase in the risk of negative effects of ionizing radiation in contrast with the expected results of biological effects' extrapolation from high to low doses.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
Externí odkaz: