[Benign mesothelial tumors].

Autor: Tischoff I; Institut für Pathologie, Ruhr-Universität Bochum an den Universitätskliniken Bergmannsheil, Bürkle-de-la-Camp Platz 1, 44789, Bochum, Deutschland. iris.tischoff@rub.de., Theile A; Institut für Pathologie, Ruhr-Universität Bochum an den Universitätskliniken Bergmannsheil, Bürkle-de-la-Camp Platz 1, 44789, Bochum, Deutschland.
Jazyk: němčina
Zdroj: Pathologie (Heidelberg, Germany) [Pathologie (Heidelb)] 2024 Sep; Vol. 45 (5), pp. 324-332. Date of Electronic Publication: 2024 May 02.
DOI: 10.1007/s00292-024-01333-6
Abstrakt: Benign mesothelial tumors are rarer than malignant mesotheliomas and are often found in the peritoneum as incidental findings in women. They include the adenomatoid tumor (AT), the well-differentiated mesothelial tumor (WDPMT), the mesothelioma in situ (MIS), and the solid papillary mesothelial tumor (SPMT). ATs are always benign and predominantly manifest in the genital tract. WDPMTs can develop multifocally and are prone to recurrence, particularly in the case of incomplete resection. Only MISs are considered a confirmed precursor lesion of malignant mesothelioma according to the currently valid World Health Organization (WHO) classifications. As with malignant mesothelioma, alterations of BAP1, MTAP, and p16 are detectable for MIS in contrast to the other three tumors. SPMTs cannot be clearly assigned to the other mesothelial tumors and have so far only been described in the peritoneum in women with a benign course.
(© 2024. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)
Databáze: MEDLINE
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