Presence of Trypanosoma cruzi TcI and Trypanosoma dionisii in sylvatic bats from Yucatan, Mexico.

Autor:	Moo-Millan JI; Laboratorio de Parasitología, Centro de Investigaciones Regionales 'Dr Hideyo Noguchi', Universidad Autónoma de Yucatán, Calle 43 #613 x 96, Col. Inalámbrica, C.P. 97225, Mérida, Yucatán, México., Tu W; Department of Tropical Medicine and Infectious Disease, School of Public Health and Tropical Medicine, and Vector-Borne and Infectious Disease Research Center, Tulane University, 1440 Canal St., 70112, New Orleans, Louisiana, USA., de Jesús Montalvo-Balam T; Laboratorio de Parasitología, Centro de Investigaciones Regionales 'Dr Hideyo Noguchi', Universidad Autónoma de Yucatán, Calle 43 #613 x 96, Col. Inalámbrica, C.P. 97225, Mérida, Yucatán, México., Ibarra-López MP; Departamento de Ecología Humana, Centro de Investigación y Estudios Avanzados del IPN (Cinvestav), Unidad Mérida, Antigua Carretera a Progreso Km 6, C.P. 97310, Mérida, Yucatán, México., Hernández-Betancourt S; Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Yucatán, Carretera Mérida-Xmatkuil Km. 15.5 Tizapán, C.P. 97100, Mérida, Yucatán, México., Jesús May-Concha I; Laboratorio de Parasitología, Centro de Investigaciones Regionales 'Dr Hideyo Noguchi', Universidad Autónoma de Yucatán, Calle 43 #613 x 96, Col. Inalámbrica, C.P. 97225, Mérida, Yucatán, México., Ibarra-Cerdeña CN; Departamento de Ecología Humana, Centro de Investigación y Estudios Avanzados del IPN (Cinvestav), Unidad Mérida, Antigua Carretera a Progreso Km 6, C.P. 97310, Mérida, Yucatán, México., Barnabé C; Institut de Recherche pour le Développement, UMR INTERTRYP IRD, CIRAD, Université de Montpellier, Campus international de Baillarguet, 34398 Montpellier Cedex 5, France., Dumonteil E; Department of Tropical Medicine and Infectious Disease, School of Public Health and Tropical Medicine, and Vector-Borne and Infectious Disease Research Center, Tulane University, 1440 Canal St., 70112, New Orleans, Louisiana, USA., Waleckx E; Laboratorio de Parasitología, Centro de Investigaciones Regionales 'Dr Hideyo Noguchi', Universidad Autónoma de Yucatán, Calle 43 #613 x 96, Col. Inalámbrica, C.P. 97225, Mérida, Yucatán, México.; Institut de Recherche pour le Développement, UMR INTERTRYP IRD, CIRAD, Université de Montpellier, Campus international de Baillarguet, 34398 Montpellier Cedex 5, France.; ACCyC, Asociación Chagas con Ciencia y Conocimiento, A. C., Sur 21 no 810, Colonia Benito Juárez, C.P. 94390, Orizaba, Veracruz, México.
Jazyk:	angličtina
Zdroj:	Transactions of the Royal Society of Tropical Medicine and Hygiene [Trans R Soc Trop Med Hyg] 2024 Oct 01; Vol. 118 (10), pp. 659-665.
DOI:	10.1093/trstmh/trae023
Abstrakt:	Background: Chagas disease is caused by Trypanosoma cruzi, whose genetic structure is divided into six discrete typing units (DTUs) known as TcI-TcVI. In the Yucatan Peninsula, Mexico, information regarding the DTUs circulating in wild mammals is scarce, while this is important knowledge for our understanding of T. cruzi transmission dynamics. Methods: In the current study, we sampled wild mammals in a sylvatic site of the Yucatan Peninsula and assessed their infection with T. cruzi by PCR. Then, for infected mammals, we amplified and sequenced nuclear and mitochondrial T. cruzi genetic markers for DTU identification. Results: In total, we captured 99 mammals belonging to the orders Chiroptera, Rodentia and Didelphimorphia. The prevalence of infection with T. cruzi was 9% (9/99; 95% CI [5, 16]), and we identified TcI in a Jamaican fruit bat, Artibeus jamaicensis. Moreover, we fortuitously identified Trypanosoma dionisii in another Jamaican fruit bat and detected an unidentified Trypanosoma species in a third specimen. While the latter discoveries were not expected because we used primers designed for T. cruzi, this study is the first to report the identification of T. dionisii in a bat from Yucatan, Mexico, adding to a recent first report of T. dionisii in bats from Veracruz, and first report of this Trypanosoma species in Mexico. Conclusion: Further research is needed to enhance our knowledge of T. cruzi DTUs and Trypanosoma diversity circulating in wildlife in Southeastern Mexico. (© The Author(s) 2024. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene.)
Databáze:	MEDLINE
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