Prevalence and Risk Factors of Cardiovascular Disease in Chronic Kidney Disease Patients at King Abdulaziz University Hospital (KAUH).

Autor:	Nabalawi RA; Nephrology, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU., Bamuflih MA; Faculty of Medicine, King Abdulaziz University, Jeddah, SAU., Farid AA; Faculty of Medicine, King Abdulaziz University, Jeddah, SAU., Almramhi KG; Internal Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU., Dawood MS; Faculty of Medicine, King Abdulaziz University, Jeddah, SAU., Ahmed MS; Faculty of Medicine, King Abdulaziz University Hospital, Jeddah, SAU., Alfawaz KS; Faculty of Medicine, King Abdulaziz University, Jeddah, SAU., Adnan AM; Faculty of Medicine, King Abdulaziz University Hospital, Jeddah, SAU.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Apr 01; Vol. 16 (4), pp. e57409. Date of Electronic Publication: 2024 Apr 01 (Print Publication: 2024).
DOI:	10.7759/cureus.57409
Abstrakt:	Background: Chronic kidney disease (CKD) has emerged as a significant global health concern, with its incidence doubling over the past three decades. Cardiovascular diseases (CVD) pose a major threat to CKD patients, surpassing the risk of progressing to end-stage renal disease. While previous studies worldwide have shed light on this association, limited research has been conducted in Saudi Arabia regarding this burden. This study aims to fill this gap by identifying the prevalence and risk factors of CVD in CKD patients at King Abdulaziz University Hospital (KAUH), Jeddah, Saudi Arabia, between 2017 and 2022. Methods: A six-year retrospective review of medical records at KAUH was conducted, including 465 non-end-stage CKD patients aged 30 to 79. Data, including demographics, clinical information, and laboratory results, were collected and statistically analyzed to investigate the association between variables. Results: Out of 465 CKD patients, 262 (56.3%) were diagnosed with CVD, with congestive heart failure and ischemic heart disease being the most common types. The majority were male 259 (55.7%), non-Saudi 278 (59.8%), and aged 60 years and older 291 (62.6%). Hypertension 394 (84.7%) and diabetes mellitus 336 (72.3%) were prevalent comorbidities. Severely reduced left ventricular ejection fraction, proteinuria, diabetes mellitus, and higher BMI were identified as significant risk factors for CVD in CKD patients. Conclusion: This research contributes valuable insights into the prevalence and risk factors of CVD in CKD patients in Saudi Arabia, emphasizing the need for early detection and intervention. The identified risk factors provide a basis for developing targeted preventive strategies to mitigate this population's CVD burden. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2024, Nabalawi et al.)
Databáze:	MEDLINE
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