Feasibility Analysis of Individualized Low Flow Rate Abdominal Contrast-Enhanced Computed Tomography in Chemotherapy Patients: Dual-Source Computed Tomography With Low Tube Voltage.

Autor:	Zhang Y; From the The Department of Radiology, The First Affiliated Hospital of Zhengzhou, University, Zhengzhou., Yuan D; From the The Department of Radiology, The First Affiliated Hospital of Zhengzhou, University, Zhengzhou., Qi K; From the The Department of Radiology, The First Affiliated Hospital of Zhengzhou, University, Zhengzhou., Zhang M; From the The Department of Radiology, The First Affiliated Hospital of Zhengzhou, University, Zhengzhou., Zhang W; From the The Department of Radiology, The First Affiliated Hospital of Zhengzhou, University, Zhengzhou., Wei N; From the The Department of Radiology, The First Affiliated Hospital of Zhengzhou, University, Zhengzhou., Li L; Siemens Healthineers, Shanghai, China., Lv P; From the The Department of Radiology, The First Affiliated Hospital of Zhengzhou, University, Zhengzhou., Gao J; From the The Department of Radiology, The First Affiliated Hospital of Zhengzhou, University, Zhengzhou., Liu J; From the The Department of Radiology, The First Affiliated Hospital of Zhengzhou, University, Zhengzhou.
Jazyk:	angličtina
Zdroj:	Journal of computer assisted tomography [J Comput Assist Tomogr] 2024 Nov-Dec 01; Vol. 48 (6), pp. 844-852. Date of Electronic Publication: 2024 May 02.
DOI:	10.1097/RCT.0000000000001624
Abstrakt:	Purpose: The aim of the study is to investigate the feasibility of using dual-source computed tomography (CT) combined with low flow rate and low tube voltage for postchemotherapy image assessment in cancer patients. Methods: Ninety patients undergoing contrast-enhanced CT scans of the upper abdomen were prospectively enrolled and randomly assigned to groups A, B, and C (n = 30 each). In group A, patients underwent scans at 120 kVp with 448 mgI/kg. Patients in group B underwent scans at 100 kVp with 336 mgI/kg. Patient in group C underwent scans at 70 kVp with of 224 mgI/kg. Quantitative measurements including the CT number, standard deviation of CT number, signal-to-noise ratio, contrast-to-noise ratio, subjective reader scores, and the volume and flow rate of contrast agent were evaluated for each group. Results: There was no statistically significant difference in the subjective image scores within the three groups except for the kidney (all P > 0.05). Group C showed significantly higher CT values, lower noise levels, and higher signal-to-noise ratio and contrast-to-noise ratio values in the majority of the regions of interest compared to the other groups ( P < 0.05). In group C, the contrast agent dose was decreased by 46% compared to group A (79.48 ± 12.24 vs 42.7 ± 8.6, P < 0.01), and the contrast agent injection rate was reduced by 22% (2.7 ± 0.41 vs 2.1 ± 0.4, P < 0.01). Conclusions: The use of 70 kVp tube voltage combined with low iodine flow rates prove to be a more effective approach in solving the challenge of compromised blood vessels in postchemotherapy tumor patients, without reducing image quality and diagnostic confidence. Competing Interests: The authors declare no conflict of interest. (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
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