Newer treatment paradigm improves outcomes in the most common neurosurgical disease of the elderly: a literature review of middle meningeal artery embolization for chronic subdural hematoma.

Autor: Debs LH; Neurosurgery Department, Medical College of Georgia, Augusta, GA, USA. ldebs@augusta.edu., Walker SE; Neurosurgery Department, Medical College of Georgia, Augusta, GA, USA., Rahimi SY; Neurosurgery Department, Medical College of Georgia, Augusta, GA, USA.
Jazyk: angličtina
Zdroj: GeroScience [Geroscience] 2024 Dec; Vol. 46 (6), pp. 6537-6561. Date of Electronic Publication: 2024 May 01.
DOI: 10.1007/s11357-024-01173-5
Abstrakt: Chronic subdural hematoma (cSDH) is one of the most prevalent neurosurgical diseases, especially in the elderly. Yet, its incidence is predicted to increase further, paralleling the growth of the geriatric population. While surgical evacuation is technically straightforward, it is associated with significant morbidity and mortality. In fact, 30% of patients are expected to have hematoma recurrence and to need repeat surgical evacuation, and 20% of patients are expected to lose independence and require long-term care. A pathophysiology more complex than originally presumed explains the disappointing results observed for decades. At its core, the formation of microcapillaries and anastomotic channels with the middle meningeal artery (MMA) perpetuates a constant cycle resulting in persistence of hematoma. The rationale behind MMA embolization is simple: to stop cSDH at its source. Over the last few years, this "newer" option has been heavily studied. It has shown tremendous potential in decreasing hematoma recurrence and improving neurological outcomes. Whether combined with surgical evacuation or performed as the only treatment, the scientific evidence to its benefits is unequivocal. Here, we aimed to review cSDH in the elderly and discuss its more recent treatment options with an emphasis on MMA embolization.
(© 2024. The Author(s).)
Databáze: MEDLINE
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