Psychopathological characteristics in ultra-high risk for psychosis with and without comorbid ADHD.

Autor: Ribolsi M; Unit of Neurology, Neurophysiology, Neurobiology and Psychiatry, Department of Medicine, Campus Bio-Medico University, Rome, Italy.; Istituto Clinico Interuniversitario - Consorzio Universitario Humanitas, Rome, Italy., Prosperi Porta D; Chair of Psychiatry, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy., Sacco R; Unit of Child & Adolescent Neuropsychiatry, Campus Bio-Medico University of Rome, Rome, Italy., Di Lorenzo G; Chair of Psychiatry, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy.; IRCCS Fondazione Santa Lucia, Rome, Italy., Fiori Nastro F; Chair of Psychiatry, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy.; IRCCS Fondazione Santa Lucia, Rome, Italy., Albergo G; Unit of Neurology, Neurophysiology, Neurobiology and Psychiatry, Department of Medicine, Campus Bio-Medico University, Rome, Italy., Di Lazzaro V; Unit of Neurology, Neurophysiology, Neurobiology and Psychiatry, Department of Medicine, Campus Bio-Medico University, Rome, Italy., Costa A; Unit of Child & Adolescent Neuropsychiatry, Campus Bio-Medico University of Rome, Rome, Italy.
Jazyk: angličtina
Zdroj: Early intervention in psychiatry [Early Interv Psychiatry] 2024 Jul; Vol. 18 (7), pp. 578-582. Date of Electronic Publication: 2024 May 01.
DOI: 10.1111/eip.13539
Abstrakt: Aim: This study investigates the psychopathological characteristics of a sample of individuals at ultra-high risk for psychosis with and without comorbid attention-deficit hyperactivity disorder (ADHD).
Methods: Twenty-eight subjects (aged 13-21 years; 13 females) with attenuated psychosis syndrome (APS) were recruited in a cross-sectional study and divided into two groups, each with 14 patients, according to the presence or absence of ADHD.
Results: The APS group showed a significantly higher prevalence of negative symptoms than the APS + ADHD group. Other characteristics investigated (positive symptoms, aberrant salience, psychotic-like experiences and prodromal symptoms) did not differ between groups.
Conclusions: The different profiles of negative symptoms in the APS with or without ADHD might suggest the presence of a specific subtype among individuals at ultra-high risk for psychosis. Longitudinal studies with larger samples will provide information about the role of negative symptoms in determining conversion to full psychosis in those people with 'pure' APS and those with APS + ADHD.
(© 2024 The Authors. Early Intervention in Psychiatry published by John Wiley & Sons Australia, Ltd.)
Databáze: MEDLINE
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