Bullous erythema multiforme secondary to fluconazole intake: A unique case report managed with photobiomodulation therapy.
| Autor: | Siqueira JM; Department of Oral Pathology, School of Dentistry, São Paulo University, Brazil.; Study Group, Laser and Health Institute, Federal University of São Paulo, Brazil., Palma LF; Department of Pathology, Federal University of São Paulo, Brazil., Campos L; Study Group, Laser and Health Institute, Federal University of São Paulo, Brazil.; Graduate Program in Implantology, School of Dentistry, University of Santo Amaro, Brazil. |
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| Jazyk: | angličtina |
| Zdroj: | National journal of maxillofacial surgery [Natl J Maxillofac Surg] 2024 Jan-Apr; Vol. 15 (1), pp. 151-153. Date of Electronic Publication: 2024 Mar 19. |
| DOI: | 10.4103/njms.njms_128_22 |
| Abstrakt: | While fluconazole use is generally considered safe and well-tolerated, there has been an increasing number of reports regarding several adverse events. Therefore, the present study aimed to present a unique case in which photobiomodulation therapy (PBMT) was employed to manage bullous erythema multiforme lesions secondary to fluconazole intake. A 32-year-old female patient sought emergency dental care due to painful orofacial lesions that had developed two days after oral fluconazole use for recurrent vulvovaginal candidiasis. Given the acute clinical features, a diagnosis of bullous erythema multiforme secondary to fluconazole was established. Prednisone 20 mg was then prescribed for five days, and fluconazole intake was immediately discontinued. As the initial treatment strategies failed to show improvement in the clinical condition, three PBMT sessions were proposed every other day. Within seven days, almost complete wound healing was observed, and any pain complaints were no longer present. The resolution of orofacial lesions within a short period suggests that PBMT could be a promising tool for managing drug-induced bullous erythema multiforme. However, more studies are needed to confirm this statement. Competing Interests: There are no conflicts of interest. (Copyright: © 2024 National Journal of Maxillofacial Surgery.) |
| Databáze: | MEDLINE |
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