Interactive parallel sex pheromone circuits that promote and suppress courtship behaviors in the cockroach.

Autor:	Tateishi K; Department of Earth System Science, Faculty of Science, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Fukuoka, Japan.; School of Biological and Environmental Sciences, Kwansei Gakuin University, 1 Gakuen Uegahara, Sanda 669-1330, Hyogo, Japan., Watanabe T; Research Center for Integrative Evolutionary Science, The Graduate University for Advanced Studies, Shonan Village, Hayama 240-0193, Kanagawa, Japan., Domae M; Research Institute for Electronic Science, Hokkaido University, Kita 12, Nishi 6, Kita-ku, Sapporo 060-0812, Hokkaido, Japan., Ugajin A; Laboratory Sector, JT Biohistory Research Hall, 1-1 Murasaki-cho, Takatsuki 569-1125, Osaka, Japan., Nishino H; Research Institute for Electronic Science, Hokkaido University, Kita 12, Nishi 6, Kita-ku, Sapporo 060-0812, Hokkaido, Japan., Nakagawa H; Department of Earth System Science, Faculty of Science, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Fukuoka, Japan., Mizunami M; Research Institute for Electronic Science, Hokkaido University, Kita 12, Nishi 6, Kita-ku, Sapporo 060-0812, Hokkaido, Japan., Watanabe H; Department of Earth System Science, Faculty of Science, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Fukuoka, Japan.
Jazyk:	angličtina
Zdroj:	PNAS nexus [PNAS Nexus] 2024 Apr 15; Vol. 3 (4), pp. pgae162. Date of Electronic Publication: 2024 Apr 15 (Print Publication: 2024).
DOI:	10.1093/pnasnexus/pgae162
Abstrakt:	Many animals use multicomponent sex pheromones for mating, but the specific function and neural processing of each pheromone component remain unclear. The cockroach Periplaneta americana is a model for studying sex pheromone communication, and an adult female emits major and minor sex pheromone components, periplanone-B and -A (PB and PA), respectively. Attraction and courtship behaviors (wing-raising and abdominal extension) are strongly expressed when adult males are exposed to PB but weakly expressed when they are exposed to PA. When major PB is presented together with minor PA, behaviors elicited by PB were impaired, indicating that PA can both promote and suppress courtship behaviors depending on the pheromonal context. In this study, we identified the receptor genes for PA and PB and investigated the effects of knocking down each receptor gene on the activities of PA- and PB-responsive sensory neurons (PA- and PB-SNs), and their postsynaptic interneurons, and as well as effects on courtship behaviors in males. We found that PB strongly and PA weakly activate PB-SNs and their postsynaptic neurons, and activation of the PB-processing pathway is critical for the expression of courtship behaviors. PA also activates PA-SNs and the PA-processing pathway. When PA and PB are simultaneously presented, the PB-processing pathway undergoes inhibitory control by the PA-processing pathway, which weakens the expression of courtship behaviors. Our data indicate that physiological interactions between the PA- and PB-processing pathways positively and negatively mediate the attraction and courtship behaviors elicited by sex pheromones. (© The Author(s) 2024. Published by Oxford University Press on behalf of National Academy of Sciences.)
Databáze:	MEDLINE
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