Bio-efficacy of Olyset ® Plus, PermaNet ® 3.0 and Interceptor ® G2 on pyrethroid-resistant populations of Anopheles gambiae s.l. prior to the June 2023 net distribution campaign in Benin, West Africa.

Autor: Zoungbédji DM; Centre de Recherche Entomologique de Cotonou (CREC), 06 BP 2604, Cotonou, Benin. davidzoungbedji91@gmail.com.; Faculté des Sciences et Techniques de l'Université d'Abomey-Calavi, Abomey-Calavi, Benin. davidzoungbedji91@gmail.com., Padonou GG; Centre de Recherche Entomologique de Cotonou (CREC), 06 BP 2604, Cotonou, Benin.; Faculté des Sciences et Techniques de l'Université d'Abomey-Calavi, Abomey-Calavi, Benin., Sovi A; Centre de Recherche Entomologique de Cotonou (CREC), 06 BP 2604, Cotonou, Benin.; Faculty of Agronomy, University of Parakou, Parakou, Benin.; Faculty of Infectious and Tropical Diseases, The London School of Hygiene and Tropical Medicine, London, UK., Konkon AK; Centre de Recherche Entomologique de Cotonou (CREC), 06 BP 2604, Cotonou, Benin.; Faculté des Sciences et Techniques de l'Université d'Abomey-Calavi, Abomey-Calavi, Benin., Salako AS; Centre de Recherche Entomologique de Cotonou (CREC), 06 BP 2604, Cotonou, Benin., Azondékon R; Centre de Recherche Entomologique de Cotonou (CREC), 06 BP 2604, Cotonou, Benin., Sidick A; Centre de Recherche Entomologique de Cotonou (CREC), 06 BP 2604, Cotonou, Benin., Ahouandjinou JM; Centre de Recherche Entomologique de Cotonou (CREC), 06 BP 2604, Cotonou, Benin., Towakinou L; Centre de Recherche Entomologique de Cotonou (CREC), 06 BP 2604, Cotonou, Benin., Ossè R; Centre de Recherche Entomologique de Cotonou (CREC), 06 BP 2604, Cotonou, Benin.; École de Gestion et d'exploitation des Systèmes d'élevage, Université Nationale d'Agriculture, Kétou, Benin., Aïkpon R; Programme National de Lutte Contre le Paludisme, Cotonou, Benin.; Université Nationale des Sciences, Technologies, Ingénierie et Mathématiques (UNSTIM), Abomey, Benin., Affoukou C; Programme National de Lutte Contre le Paludisme, Cotonou, Benin., Baba-Moussa L; Faculté des Sciences et Techniques de l'Université d'Abomey-Calavi, Abomey-Calavi, Benin.; Laboratoire de Biologie et de Typage Moléculaire en Microbiologie (LBTMM), département de Biochimie et de Biologie Cellulaire (BBC), Université de Abomey-Calavi (UAC), Abomey-Calavi, Benin., Akogbéto M; Centre de Recherche Entomologique de Cotonou (CREC), 06 BP 2604, Cotonou, Benin.
Jazyk: angličtina
Zdroj: Tropical medicine and health [Trop Med Health] 2024 Apr 30; Vol. 52 (1), pp. 34. Date of Electronic Publication: 2024 Apr 30.
DOI: 10.1186/s41182-024-00599-z
Abstrakt: Background: This study investigates the effectiveness of new-generation mosquito nets, like Olyset ® Plus and PermaNet ® 3.0, and dual-action nets such as Interceptor ® G2, against pyrethroid-resistant Anopheles gambiae mosquitoes following the 2023 mass distribution of long-lasting insecticidal nets in Benin.
Methods: We tested wild mosquito populations from six communes in Benin against various pyrethroid (permethrin 0.75%, alphacypermethrin 0.05%, and deltamethrin 0.05%) using WHO tube tests. Additionally, we exposed mosquitoes to chlorfenapyr 100 µg/ml using the CDC bottle bioassay method. A subset of mosquitoes underwent biochemical and PCR tests to check the overexpression of metabolic enzymes and the Kdr L1014F mutation. We evaluated the effectiveness of Olyset ® Plus, PermaNet ® 3.0, and Interceptor ® G2 nets using cone and tunnel tests on both laboratory and field populations of An. gambiae.
Results: Overall, the highest mortality rate was 60% with pyrethroid and 98 to100% with chlorfenapyr. In cone tests, all three types of nets induced mortality rates above 80% in the susceptible laboratory strain of An. gambiae. Notably, Olyset ® Plus showed the highest mortality rates for pyrethroid-resistant mosquitoes in cone tests, ranging from 81.03% (95% CI: 68.59-90.13) in Djougou to 96.08% (95% CI: 86.54-99.52) in Akpro-Missérété. PermaNet ® 3.0 had variable rates, from 42.5% (95% CI: 27.04-59.11) in Djougou to 58.54% (95% CI: 42.11-73.68) in Porto-Novo. However, revealed good results for Interceptor ® G2, with 94% (95% CI: 87.40-97.77) mortality and 89.09% blood sampling inhibition in local populations of An. gambiae. In comparison, Interceptor ® had lower rates of 17% (95% CI: 10.23-25.82) and 60%, respectively.
Conclusion: These results suggest that tunnel tests are effective for evaluating dual-active ingredient nets. Additionally, Interceptor ® G2 and PBO nets like Olyset ® Plus could be considered as alternatives against pyrethroid-resistant mosquitoes.
(© 2024. The Author(s).)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje