Colostrum as a source of ESBL-Escherichia coli in feces of newborn calves.

Autor: Bachmann L; University of Applied Science Neubrandenburg, Brodaer Str. 2, 17033, Neubrandenburg, Germany. bachmann@hs-nb.de.; Research Institute of Farm Animal Biology (FBN), Dummerstorf, Germany. bachmann@hs-nb.de., Weber L; University of Applied Science Neubrandenburg, Brodaer Str. 2, 17033, Neubrandenburg, Germany., Liermann W; Research Institute of Farm Animal Biology (FBN), Dummerstorf, Germany., Hammon HM; Research Institute of Farm Animal Biology (FBN), Dummerstorf, Germany., Delling C; Institute for Parasitology, School of Veterinary Medicine, University of Leipzig, Leipzig, Germany., Dengler F; Institute of Physiology, University of Leipzig, Leipzig, Germany.; Institute of Physiology, Pathophysiology and Biophysics, University of Veterinary Medicine Vienna, Vienna, Austria., Schaufler K; Institute of Pharmacy, University of Greifswald, Greifswald, Germany.; Department Epidemiology and Ecology of Antimicrobial Resistance, Helmholtz Centre for Infection Research, Helmholtz Institute for One Health, Greifswald, Germany.; Institute of Infection Medicine, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Schwabe M; Institute of Pharmacy, University of Greifswald, Greifswald, Germany., Eger E; Department Epidemiology and Ecology of Antimicrobial Resistance, Helmholtz Centre for Infection Research, Helmholtz Institute for One Health, Greifswald, Germany., Becker K; Friedrich Loeffler-Institute of Medical Microbiology, University Medicine Greifswald, Greifswald, Germany., Schütz A; Institute of Epidemiology, Friedrich-Loeffler-Institute, Greifswald, Insel Riems, Germany., Homeier-Bachmann T; Institute of Epidemiology, Friedrich-Loeffler-Institute, Greifswald, Insel Riems, Germany.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2024 Apr 30; Vol. 14 (1), pp. 9929. Date of Electronic Publication: 2024 Apr 30.
DOI: 10.1038/s41598-024-60461-4
Abstrakt: The aim of the present study was to determine if colostrum and the equipment for harvesting and feeding colostrum are sources of fecal ESBL/AmpC-producing Escherichia coli (ESBL/AmpC-E. coli) in calves. Therefore, 15 male calves fed with pooled colostrum on a dairy farm and held individually in an experimental barn, the colostrum pool and the equipment for harvesting and feeding colostrum were sampled and analyzed for the occurrence of ESBL/AmpC-E. coli. The ESBL-AmpC-E. coli suspicious isolates were subjected to whole-genome sequence analysis. Forty-three of 45 fecal samples were tested positive for ESBL/AmpC-E. coli. In the colostrum sample and in the milking pot, we also found ESBL/AmpC-E. coli. All 45 E. coli isolates were ESBL-producers, mainly commensal sequence type (ST) 10, but also human-extraintestinal pathogenic E. coli ST131 and ST117 were found. The clonal identity of six fecal isolates with the ESBL-E. coli isolate from the colostrum and of five fecal isolates with the strain from the milking pot demonstrates that the hygiene of colostrum or the colostrum equipment can play a significant role in the spread of ESBL-E. coli. Effective sanitation procedures for colostrum harvesting and feeding equipment are crucial to reduce the ESBL-E. coli shedding of neonatal dairy calves.
(© 2024. The Author(s).)
Databáze: MEDLINE
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