[Extracorporeal Membrane Oxygenation Combined With Interventional Thrombectomy for Treating High-Risk Pulmonary Embolism Caused by Protein C Deficiency:Report of One Case].

Autor:	Xie YH; 1 Department of Critical Care Medicine,The Second Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China., Zhang A; 1 Department of Critical Care Medicine,The Second Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China., Zeng HQ; 2 Department of Hematology,The Second Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China., Cao YX; 1 Department of Critical Care Medicine,The Second Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China.
Jazyk:	čínština
Zdroj:	Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae [Zhongguo Yi Xue Ke Xue Yuan Xue Bao] 2024 Apr; Vol. 46 (2), pp. 293-296.
DOI:	10.3881/j.issn.1000-503X.15662
Abstrakt:	Hereditary protein C deficiency is a chromosomal genetic disease caused by mutations in the protein C gene,which can lead to venous thrombosis and is mostly related to mutations in exons 4-9 and intron 8.Fatal pulmonary embolism caused by mutations in the protein C gene is rare,and the treatment faces great challenges.This article reports a case of fatal pulmonary embolism caused by a frameshift mutation in exon 8 of the protein C gene and summarizes the treatment experience of combining extracorporeal membrane oxygenation (for respiratory and circulatory support) with interventional thrombectomy,providing a basis for the diagnosis and treatment of this disease.
Databáze:	MEDLINE
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