Increases in regional brain volume across two native South American male populations.

Autor: Chaudhari NN; Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, USA.; Ethel Percy Andrus Gerontology Center, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Imms PE; Ethel Percy Andrus Gerontology Center, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Chowdhury NF; Ethel Percy Andrus Gerontology Center, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA., Gatz M; Center for Economic and Social Research, Dana and David Dornsife College of Letters, Arts and Sciences, University of Southern California, Los Angeles, CA, USA., Trumble BC; Center for Evolution & Medicine, School of Human Evolution and Social Change, School of Life Sciences, Arizona State University, Tempe, AZ, USA., Mack WJ; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Law EM; iBRAIN Research Laboratory, Departments of Neuroscience, Computer Systems and Electrical Engineering, Monash University, Melbourne, VIC, Australia.; Department of Radiology, The Alfred Health Hospital, Melbourne, VIC, Australia.; Department of Neurology, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA., Sutherland ML; MemorialCare Health Systems, Fountain Valley, CA, USA., Sutherland JD; MemorialCare Health Systems, Fountain Valley, CA, USA., Rowan CJ; Renown Institute for Heart and Vascular Health, Reno, NV, USA.; School of Medicine, University of Nevada, Reno, NV, USA., Wann LS; Division of Cardiology, University of New Mexico, Albuquerque, NM, USA., Allam AH; Department of Cardiology, School of Medicine, Al-Azhar University, Al Mikhaym Al Daem, Cairo, Egypt., Thompson RC; Saint Luke's Mid America Heart Institute, University of Missouri, Kansas City, MO, USA., Michalik DE; Department of Pediatrics, School of Medicine, University of California, Irvine, Orange, CA, USA.; MemorialCare Miller Children's & Women's Hospital, Long Beach Medical Center, Long Beach, CA, USA., Miyamoto M; Division of Cardiology, Mission Heritage Medical Group, Providence Health, Mission Viejo, CA, USA., Lombardi G; Universidad Peruana Cayetano Heredia, Lima, Peru., Cummings DK; Department of Anthropology, University of New Mexico, Albuquerque, NM, USA.; Economic Science Institute, Argyros School of Business and Economics, Chapman University, Orange, CA, USA., Seabright E; Department of Anthropology, University of New Mexico, Albuquerque, NM, USA., Alami S; Department of Anthropology, University of New Mexico, Albuquerque, NM, USA., Garcia AR; Center for Evolution & Medicine, School of Human Evolution and Social Change, School of Life Sciences, Arizona State University, Tempe, AZ, USA., Rodriguez DE; Institute of Biomedical Research, San Simon University, Cochabamba, Bolivia., Gutierrez RQ; Tsimane Health and Life History Project, San Borja, Beni, Bolivia., Copajira AJ; Tsimane Health and Life History Project, San Borja, Beni, Bolivia., Hooper PL; Department of Anthropology, University of New Mexico, Albuquerque, NM, USA., Buetow KH; Center for Evolution & Medicine, School of Human Evolution and Social Change, School of Life Sciences, Arizona State University, Tempe, AZ, USA., Stieglitz J; Institute for Advanced Study in Toulouse, Toulouse 1 Capitol University, Toulouse, France., Gurven MD; Department of Anthropology, University of California, Santa Barbara, USA., Thomas GS; MemorialCare Health Systems, Fountain Valley, CA, USA.; Division of Cardiology, University of California, Irvine, Orange, CA, USA., Kaplan HS; Economic Science Institute, Argyros School of Business and Economics, Chapman University, Orange, CA, USA., Finch CE; Ethel Percy Andrus Gerontology Center, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.; Departments of Biological Sciences, Anthropology and Psychology, Dana and David Dornsife College of Letters, Arts and Sciences, University of Southern California, Los Angeles, CA, USA., Irimia A; Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, USA. irimia@usc.edu.; Ethel Percy Andrus Gerontology Center, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA. irimia@usc.edu.; Department of Quantitative and Computational Biology, Dana and David Dornsife College of Letters, Arts and Sciences, University of Southern California, Los Angeles, CA, USA. irimia@usc.edu.
Jazyk: angličtina
Zdroj: GeroScience [Geroscience] 2024 Oct; Vol. 46 (5), pp. 4563-4583. Date of Electronic Publication: 2024 Apr 29.
DOI: 10.1007/s11357-024-01168-2
Abstrakt: Industrialized environments, despite benefits such as higher levels of formal education and lower rates of infections, can also have pernicious impacts upon brain atrophy. Partly for this reason, comparing age-related brain volume trajectories between industrialized and non-industrialized populations can help to suggest lifestyle correlates of brain health. The Tsimane, indigenous to the Bolivian Amazon, derive their subsistence from foraging and horticulture and are physically active. The Moseten, a mixed-ethnicity farming population, are physically active but less than the Tsimane. Within both populations (N = 1024; age range = 46-83), we calculated regional brain volumes from computed tomography and compared their cross-sectional trends with age to those of UK Biobank (UKBB) participants (N = 19,973; same age range). Surprisingly among Tsimane and Moseten (T/M) males, some parietal and occipital structures mediating visuospatial abilities exhibit small but significant increases in regional volume with age. UKBB males exhibit a steeper negative trend of regional volume with age in frontal and temporal structures compared to T/M males. However, T/M females exhibit significantly steeper rates of brain volume decrease with age compared to UKBB females, particularly for some cerebro-cortical structures (e.g., left subparietal cortex). Across the three populations, observed trends exhibit no interhemispheric asymmetry. In conclusion, the age-related rate of regional brain volume change may differ by lifestyle and sex. The lack of brain volume reduction with age is not known to exist in other human population, highlighting the putative role of lifestyle in constraining regional brain atrophy and promoting elements of non-industrialized lifestyle like higher physical activity.
(© 2024. The Author(s).)
Databáze: MEDLINE
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