Antibacterial activity of flavonoid extracts from Enteromorpha intestinalis and Caulerpa prolifera against multidrug-resistant foodborne bacterial isolates.

Autor:	Alghazeer RO; Biochemistry Division, Chemistry Department, Faculty of Sciences, University of Tripoli, Tripoli, Libya., Azwai SM; Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Tripoli, Tripoli, Libya., Elmansori AA; Botany Department, Faculty of Sciences, University of Tripoli, Tripoli, Libya., Alzintani KM; Department of Botany, Faculty of Science, Al Zintan University, Zintan, Libya., Elghmasi S; Department of Biochemistry, Faculty of Medicine, University of Tripoli, Tripoli, Libya., Alnajjar AY; Department of Soil and Water, Faculty of Agriculture, University of Tripoli, Tripoli, Libya., Gammoudi FT; Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Tripoli, Tripoli, Libya., Sidati M; Biotechnology Lab, Marin Biology Research Center, Tajura-East of Tripoli, Tripoli, Libya., Hawisa ST; Department of Periodontology, Dental College, University of Tripoli, Tripoli, Libya., Garbaj AM; Department of Food Hygiene, Faculty of Veterinary Medicine, University of Tripoli, Tripoli, Libya., Eldaghayes IM; Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Tripoli, Tripoli, Libya.
Jazyk:	angličtina
Zdroj:	Open veterinary journal [Open Vet J] 2024 Mar; Vol. 14 (3), pp. 769-778. Date of Electronic Publication: 2024 Mar 31.
DOI:	10.5455/OVJ.2024.v14.i3.3
Abstrakt:	Background: Food poisoning caused by bacterial agents is a worldwide problem, usually accompanied by unpleasant symptoms and may be severe leading to death. Natural compounds from marine algae namely flavonoids may play a role in the remedy of this condition. Aim: This research aims to assess the potency of flavonoids extracted from Enteromorpha intestinalis and Caulerpa prolifera as antibacterial agents. Methods: Enteromorpha intestinalis was collected from Western Libyan Coast and C. prolifera was collected from Farwa Island. The antimicrobial activity and determination of minimum inhibitory concentration of algal flavonoid-containing extracts was performed in vitro against some positive and negative Gram bacteria. Results: Crude extract containing flavonoids from E. intestinalis was more effective than C. prolifera extract against Staphylococcus aureus with antimicrobial essay (25-28 + 1 and 14.5-37.5 + 0.5-1.5), MIC (50 and 50-250 µg/ml), MBC (75 and 75-250 µg/ml). In Bacillus cereus, the antimicrobial assay (19-24.5 + 0.5-1.5: 24 + 1), MIC (50-250 + 100 µg/ml), and MBC (250 and 125 µg/ml). On the other hand, flavonoids containing extract from C. prolifera were more effective than E. intestinalis against Enterohemorrhagic Escherichia coli O157 EHEC O157 (25-28 + 1: 14-18.5 + 0.5-1.5), MIC (100-250:100-500 µg/ml), and MBC (150-250 and 250-500 µg/ml). Salmonella enterica qualitatively combat by flavonoid from E. intestinalis (13.5-14 + 0.5-1: 10.5-13.5 + 0.5-1.5), MIC (100-250: 250 µg/ml), and MBC (100-250: 250 µg/ml). Flavonoids from C. prolifera (4 strains: 2 strains) were effective against S. enterica. Crude flavonoids from both algae were not effective against Bacillus pumilus. Conclusion: Data from this study could conclude that flavonoid extracts from E. intestinalis and C. prolifera could be used against foodborne bacterial agents. Competing Interests: All authors declare that there is no conflict of interest.
Databáze:	MEDLINE
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