Clinic-Based Characterization of Adolescents and Young Adults With Migraine: Psychological Functioning, Headache Days, and Disability.

Autor:	Gibler RC; Division of Behavioral Medicine and Clinical Psychology (RCG, MAM, JP, BLR, MME, SWP, SKS); Headache Center (RCG, MAM, BLR, SWP, MKS, JK, ADH, SKS), Cincinnati Children's Hospital Medical Center; now with the Department of Pediatrics (RCG), University of Kansas Medical Center, Kansas City, KS; Department of Pediatrics (JP, BLR, MME, SWP, MKS, JK, ADH, SKS), University of Cincinnati College of Medicine, OH; Clinical Child and Adolescent Psychology (MLD), Norton Children's Hospital; University of Louisville School of Medicine (MLD), KY; Division of Neurology (MKS, JK, ADH), Cincinnati Children's Hospital Medical Center; and Headache Center of Hope (HOB), Cincinnati, OH., Marzouk MA; Division of Behavioral Medicine and Clinical Psychology (RCG, MAM, JP, BLR, MME, SWP, SKS); Headache Center (RCG, MAM, BLR, SWP, MKS, JK, ADH, SKS), Cincinnati Children's Hospital Medical Center; now with the Department of Pediatrics (RCG), University of Kansas Medical Center, Kansas City, KS; Department of Pediatrics (JP, BLR, MME, SWP, MKS, JK, ADH, SKS), University of Cincinnati College of Medicine, OH; Clinical Child and Adolescent Psychology (MLD), Norton Children's Hospital; University of Louisville School of Medicine (MLD), KY; Division of Neurology (MKS, JK, ADH), Cincinnati Children's Hospital Medical Center; and Headache Center of Hope (HOB), Cincinnati, OH., Peugh J; Division of Behavioral Medicine and Clinical Psychology (RCG, MAM, JP, BLR, MME, SWP, SKS); Headache Center (RCG, MAM, BLR, SWP, MKS, JK, ADH, SKS), Cincinnati Children's Hospital Medical Center; now with the Department of Pediatrics (RCG), University of Kansas Medical Center, Kansas City, KS; Department of Pediatrics (JP, BLR, MME, SWP, MKS, JK, ADH, SKS), University of Cincinnati College of Medicine, OH; Clinical Child and Adolescent Psychology (MLD), Norton Children's Hospital; University of Louisville School of Medicine (MLD), KY; Division of Neurology (MKS, JK, ADH), Cincinnati Children's Hospital Medical Center; and Headache Center of Hope (HOB), Cincinnati, OH., Reidy BL; Division of Behavioral Medicine and Clinical Psychology (RCG, MAM, JP, BLR, MME, SWP, SKS); Headache Center (RCG, MAM, BLR, SWP, MKS, JK, ADH, SKS), Cincinnati Children's Hospital Medical Center; now with the Department of Pediatrics (RCG), University of Kansas Medical Center, Kansas City, KS; Department of Pediatrics (JP, BLR, MME, SWP, MKS, JK, ADH, SKS), University of Cincinnati College of Medicine, OH; Clinical Child and Adolescent Psychology (MLD), Norton Children's Hospital; University of Louisville School of Medicine (MLD), KY; Division of Neurology (MKS, JK, ADH), Cincinnati Children's Hospital Medical Center; and Headache Center of Hope (HOB), Cincinnati, OH., Ernst MM; Division of Behavioral Medicine and Clinical Psychology (RCG, MAM, JP, BLR, MME, SWP, SKS); Headache Center (RCG, MAM, BLR, SWP, MKS, JK, ADH, SKS), Cincinnati Children's Hospital Medical Center; now with the Department of Pediatrics (RCG), University of Kansas Medical Center, Kansas City, KS; Department of Pediatrics (JP, BLR, MME, SWP, MKS, JK, ADH, SKS), University of Cincinnati College of Medicine, OH; Clinical Child and Adolescent Psychology (MLD), Norton Children's Hospital; University of Louisville School of Medicine (MLD), KY; Division of Neurology (MKS, JK, ADH), Cincinnati Children's Hospital Medical Center; and Headache Center of Hope (HOB), Cincinnati, OH., Daffin ML; Division of Behavioral Medicine and Clinical Psychology (RCG, MAM, JP, BLR, MME, SWP, SKS); Headache Center (RCG, MAM, BLR, SWP, MKS, JK, ADH, SKS), Cincinnati Children's Hospital Medical Center; now with the Department of Pediatrics (RCG), University of Kansas Medical Center, Kansas City, KS; Department of Pediatrics (JP, BLR, MME, SWP, MKS, JK, ADH, SKS), University of Cincinnati College of Medicine, OH; Clinical Child and Adolescent Psychology (MLD), Norton Children's Hospital; University of Louisville School of Medicine (MLD), KY; Division of Neurology (MKS, JK, ADH), Cincinnati Children's Hospital Medical Center; and Headache Center of Hope (HOB), Cincinnati, OH., Powers SW; Division of Behavioral Medicine and Clinical Psychology (RCG, MAM, JP, BLR, MME, SWP, SKS); Headache Center (RCG, MAM, BLR, SWP, MKS, JK, ADH, SKS), Cincinnati Children's Hospital Medical Center; now with the Department of Pediatrics (RCG), University of Kansas Medical Center, Kansas City, KS; Department of Pediatrics (JP, BLR, MME, SWP, MKS, JK, ADH, SKS), University of Cincinnati College of Medicine, OH; Clinical Child and Adolescent Psychology (MLD), Norton Children's Hospital; University of Louisville School of Medicine (MLD), KY; Division of Neurology (MKS, JK, ADH), Cincinnati Children's Hospital Medical Center; and Headache Center of Hope (HOB), Cincinnati, OH., Kabbouche Samaha M; Division of Behavioral Medicine and Clinical Psychology (RCG, MAM, JP, BLR, MME, SWP, SKS); Headache Center (RCG, MAM, BLR, SWP, MKS, JK, ADH, SKS), Cincinnati Children's Hospital Medical Center; now with the Department of Pediatrics (RCG), University of Kansas Medical Center, Kansas City, KS; Department of Pediatrics (JP, BLR, MME, SWP, MKS, JK, ADH, SKS), University of Cincinnati College of Medicine, OH; Clinical Child and Adolescent Psychology (MLD), Norton Children's Hospital; University of Louisville School of Medicine (MLD), KY; Division of Neurology (MKS, JK, ADH), Cincinnati Children's Hospital Medical Center; and Headache Center of Hope (HOB), Cincinnati, OH., Kacperski J; Division of Behavioral Medicine and Clinical Psychology (RCG, MAM, JP, BLR, MME, SWP, SKS); Headache Center (RCG, MAM, BLR, SWP, MKS, JK, ADH, SKS), Cincinnati Children's Hospital Medical Center; now with the Department of Pediatrics (RCG), University of Kansas Medical Center, Kansas City, KS; Department of Pediatrics (JP, BLR, MME, SWP, MKS, JK, ADH, SKS), University of Cincinnati College of Medicine, OH; Clinical Child and Adolescent Psychology (MLD), Norton Children's Hospital; University of Louisville School of Medicine (MLD), KY; Division of Neurology (MKS, JK, ADH), Cincinnati Children's Hospital Medical Center; and Headache Center of Hope (HOB), Cincinnati, OH., Hershey AD; Division of Behavioral Medicine and Clinical Psychology (RCG, MAM, JP, BLR, MME, SWP, SKS); Headache Center (RCG, MAM, BLR, SWP, MKS, JK, ADH, SKS), Cincinnati Children's Hospital Medical Center; now with the Department of Pediatrics (RCG), University of Kansas Medical Center, Kansas City, KS; Department of Pediatrics (JP, BLR, MME, SWP, MKS, JK, ADH, SKS), University of Cincinnati College of Medicine, OH; Clinical Child and Adolescent Psychology (MLD), Norton Children's Hospital; University of Louisville School of Medicine (MLD), KY; Division of Neurology (MKS, JK, ADH), Cincinnati Children's Hospital Medical Center; and Headache Center of Hope (HOB), Cincinnati, OH., O'Brien H; Division of Behavioral Medicine and Clinical Psychology (RCG, MAM, JP, BLR, MME, SWP, SKS); Headache Center (RCG, MAM, BLR, SWP, MKS, JK, ADH, SKS), Cincinnati Children's Hospital Medical Center; now with the Department of Pediatrics (RCG), University of Kansas Medical Center, Kansas City, KS; Department of Pediatrics (JP, BLR, MME, SWP, MKS, JK, ADH, SKS), University of Cincinnati College of Medicine, OH; Clinical Child and Adolescent Psychology (MLD), Norton Children's Hospital; University of Louisville School of Medicine (MLD), KY; Division of Neurology (MKS, JK, ADH), Cincinnati Children's Hospital Medical Center; and Headache Center of Hope (HOB), Cincinnati, OH., Slater SK; Division of Behavioral Medicine and Clinical Psychology (RCG, MAM, JP, BLR, MME, SWP, SKS); Headache Center (RCG, MAM, BLR, SWP, MKS, JK, ADH, SKS), Cincinnati Children's Hospital Medical Center; now with the Department of Pediatrics (RCG), University of Kansas Medical Center, Kansas City, KS; Department of Pediatrics (JP, BLR, MME, SWP, MKS, JK, ADH, SKS), University of Cincinnati College of Medicine, OH; Clinical Child and Adolescent Psychology (MLD), Norton Children's Hospital; University of Louisville School of Medicine (MLD), KY; Division of Neurology (MKS, JK, ADH), Cincinnati Children's Hospital Medical Center; and Headache Center of Hope (HOB), Cincinnati, OH.
Jazyk:	angličtina
Zdroj:	Neurology. Clinical practice [Neurol Clin Pract] 2024 Jun; Vol. 14 (3), pp. e200294. Date of Electronic Publication: 2024 Apr 24.
DOI:	10.1212/CPJ.0000000000200294
Abstrakt:	Background and Objectives: This cross-sectional observational study retrospectively examined clinical data collected from adolescents and young adults (AYAs) seeking care in a specialty headache clinic. We characterized participants' headache characteristics and psychological functioning and examined the association between self-reported anxiety and depressive symptoms and headache frequency, severity, and disability. Methods: During their clinic visit, AYAs ( M age = 18.36; range = 14-32, 79.5% female) completed an intake questionnaire and reported about their headache characteristics (i.e., frequency, severity, and duration of symptoms in months), mental health history (i.e., previous diagnosis of an anxiety or depressive disorder), and utilization of emergency department (ED) services for migraine. AYAs also completed psychometrically validated screening tools for anxiety and depressive symptoms (i.e., the GAD-7 and PHQ-9). We computed descriptive statistics and examined associations among scores on psychological measures and headache characteristics, including migraine-related disability. We also tested whether individuals with clinically elevated GAD-7 and PHQ-9 scores had higher levels of disability relative to those with fewer/subclinical levels of anxiety and depressive symptoms. Results: Participants ( N = 283) reported more than 19 headache days per month on average, with more than 90% describing their average headache intensity as moderate or severe . Nearly half of AYAs reported severe headache-related disability. Approximately one-quarter of AYAs reported a previous diagnosis anxiety or depressive disorder diagnosis, and more than one-third scored above clinical cutoffs on the PHQ-9 and GAD-7. Higher scores on both psychological screening instruments were associated with greater headache frequency. More than 10% of patients endorsed current suicidal ideation; this was not related to headache-related disability. Participants reported a high degree of ED utilization for headache; these rates were unrelated to endorsement of psychological comorbidities. Discussion: In this sample of AYAs, headache characteristics were generally unrelated to scores on measures on psychological functioning. However, the observed rates of clinically elevated anxiety/depressive symptoms and suicidality in this sample of AYAs underscore the importance of screening for psychological comorbidities in neurology clinics that serve this age group, irrespective of self-reported disability. Results also emphasize the need to expand access to behavioral health services for AYAs with headache disorders and the importance of incorporating a biopsychosocial perspective to the transition of health care from pediatrics to adult neurology practice. Competing Interests: R.C. Gibler and M.A. Marzouk report support from a training grant through the National Institute for Diabetes and Digestive and Kidney Diseases (T32DK063929). All other authors report no disclosures relevant to the manuscript. Full disclosure form information provided by the authors is available with the full text of this article at Neurology.org/cp. (© 2024 American Academy of Neurology.)
Databáze:	MEDLINE
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