Multifocal Primary Extranodal Non-Hodgkin Lymphoma: A Report of a Rare Case.

Autor: Kani V; Department of Pathology, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND., Ravichandran A; Department of Pathology, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND., Grace Priyadarshini S; Department of Pathology, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND., Diwagar N; Department of Pathology, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND., Esakki M; Department of Pathology, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Mar 28; Vol. 16 (3), pp. e57105. Date of Electronic Publication: 2024 Mar 28 (Print Publication: 2024).
DOI: 10.7759/cureus.57105
Abstrakt: Primary extranodal non-Hodgkin lymphoma (NHL) is a rare manifestation of lymphoid malignancies and typically arises in tissues outside the lymph nodes and can involve various organs and anatomical sites presenting unique challenges in diagnosis and treatment. Multifocal primary extranodal NHL, characterized by simultaneous involvement of multiple extranodal sites, presents a diagnostic and therapeutic challenge due to its uncommon presentation and varied clinical manifestations. Despite advances in diagnostic modalities and treatment strategies for NHL, multifocal involvement poses unique clinical dilemmas requiring a multidisciplinary approach for accurate diagnosis and optimal therapeutic intervention. In this case report, we describe a rare case of multifocal primary extranodal NHL in a 29-year-old female, highlighting the complexities associated with its diagnosis and management. Through this case presentation, we aim to underscore the importance of recognizing and addressing the intricacies of multifocal primary extranodal NHL to enhance clinical outcomes and improve patient care. It also highlights the diagnostic complexity and clinical challenges associated with multifocal primary extranodal NHL. A multidisciplinary approach involving haematologists, oncologists, radiologists, and pathologists is crucial for the accurate diagnosis and optimal management of such cases. Additionally, further research is warranted to better understand the underlying pathogenesis and improve treatment strategies for this rare presentation of NHL.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2024, Kani et al.)
Databáze: MEDLINE