Eschar in a Belgian traveler returning from Central Europe.

Autor: Costescu Strachinaru DI; Center for Infectious Diseases, Queen Astrid Military Hospital, Rue Bruyn 1, 1120, Brussels, Belgium., Henckaerts L; Department of General Internal Medicine, KU Leuven, University Hospitals Leuven, Herestraat 49, Leuven, Belgium.; Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical Bacteriology and Mycology, KU Leuven, University Hospitals Leuven, Herestraat 49, Leuven, Belgium., Depypere M; Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical Bacteriology and Mycology, KU Leuven, University Hospitals Leuven, Herestraat 49, Leuven, Belgium.; University Hospitals Leuven, Department of laboratory medicine, B-3000, KU Leuven, University Hospitals Leuven, Herestraat 49, Leuven, Belgium., Vanbrabant P; Center for Infectious Diseases, Queen Astrid Military Hospital, Rue Bruyn 1, 1120, Brussels, Belgium.; Department of General Internal Medicine, KU Leuven, University Hospitals Leuven, Herestraat 49, Leuven, Belgium.
Jazyk: angličtina
Zdroj: Oxford medical case reports [Oxf Med Case Reports] 2024 Apr 25; Vol. 2024 (4), pp. omae032. Date of Electronic Publication: 2024 Apr 25 (Print Publication: 2024).
DOI: 10.1093/omcr/omae032
Abstrakt: Background: Tularemia is a zoonotic infection caused by Francisella tularensis , an aerobic, facultative intracellular coccobacillus, encountered especially in the Northern hemisphere. F. tularensis is a pathogen of humans and hundreds of animal species.
Patients and Methods: A Belgian traveler returning from an adventurous vacation in Central Europe presents fever, flu-like symptoms, a skin ulcer with a necrotic center resembling an eschar on the left thigh and painful left inguinal lymphadenopathy. An enzyme linked immunosorbent assay developed by the National Reference Laboratory for Tularemia, Sciensano, Belgium, detected elevated Ig G antibodies against F. tularensis , while the rest of the serologies were negative.
Results: A highly likely case of ulceroglandular tularemia is described and the differential diagnosis is discussed.
Conclusion: The incidence of tularemia has been increasing throughout Europe in recent years. Physicians should be aware of this disease, its diversity of reservoirs, transmission routes and clinical presentations.
Competing Interests: No conflicts of interest.
(© The Author(s) 2024. Published by Oxford University Press.)
Databáze: MEDLINE
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