Impact of PVC microplastics in photodynamic inactivation of Staphylococcus aureus and MRSA.

Autor:	Lima AR; Laboratory of Environmental Biophotonics, São Carlos Institute of Physics, University of São Paulo, São Carlos, SP, Brazil E-mail: alessandra_lima@usp.br., Sammarro Silva KJ; Laboratory of Environmental Biophotonics, São Carlos Institute of Physics, University of São Paulo, São Carlos, SP, Brazil., Aguiar ASN; Grupo de Química Teórica e Estrutural de Anápolis, Universidade Estadual de Goiás, Anápolis, GO, Brazil; Laboratório de Novos Materiais, Universidade Evangélica de Goiás, Anápolis, GO, Brazil., de Souza M; Laboratory of Environmental Biophotonics, São Carlos Institute of Physics, University of São Paulo, São Carlos, SP, Brazil., Lima THN; Laboratory of Environmental Biophotonics, São Carlos Institute of Physics, University of São Paulo, São Carlos, SP, Brazil., Blanco KC; Laboratory of Environmental Biophotonics, São Carlos Institute of Physics, University of São Paulo, São Carlos, SP, Brazil., Bagnato VS; Laboratory of Environmental Biophotonics, São Carlos Institute of Physics, University of São Paulo, São Carlos, SP, Brazil; Department of Biomedical Engineering, Texas A&M University, College Station, TX, USA., Dias LD; Laboratório de Novos Materiais, Universidade Evangélica de Goiás, Anápolis, GO, Brazil.
Jazyk:	angličtina
Zdroj:	Water science and technology : a journal of the International Association on Water Pollution Research [Water Sci Technol] 2024 Apr; Vol. 89 (8), pp. 2105-2117. Date of Electronic Publication: 2024 Mar 29.
DOI:	10.2166/wst.2024.104
Abstrakt:	Photodynamic processes have found widespread application in therapies. These processes involve photosensitizers (PSs) that, when excited by specific light wavelengths and in the presence of molecular oxygen, generate reactive oxygen species (ROS), that target cells leading to inactivation. Photodynamic action has gained notable attention in environmental applications, particularly against pathogens and antibiotic-resistant bacteria (ARB) that pose a significant challenge to public health. However, environmental matrices frequently encompass additional contaminants and interferents, including microplastics (MPs), which are pollutants of current concern. Their presence in water and effluents has been extensively documented, highlighting their impact on conventional treatment methods, but this information remains scarce in the context of photodynamic inactivation (PDI) setups. Here, we described the effects of polyvinyl chloride (PVC) microparticles in PDI targeting Staphylococcus aureus and its methicillin-resistant strain (MRSA), using curcumin as a PS under blue light. The presence of PVC microparticles does not hinder ROS formation; however, depending on its concentration, it can impact bacterial inactivation. Our results underscore that PDI remains a potent method for reducing bacterial concentrations in water and wastewater containing ARB, even in highly contaminated scenarios with MPs. Competing Interests: The authors declare there is no conflict. (© 2024 The Authors This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (CC BY 4.0), which permits copying, adaptation and redistribution, provided the original work is properly cited (http://creativecommons.org/licenses/by/4.0/).)
Databáze:	MEDLINE
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