Detection of SARS-CoV-2 RNA in a Zoo-Kept Red Fox ( Vulpes vulpes ).

Autor: Chan T; Clinical Laboratory, Department of Clinical Diagnostics and Services, and Center for Clinical Studies, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland., Ginders J; Clinical Laboratory, Department of Clinical Diagnostics and Services, and Center for Clinical Studies, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland., Kuhlmeier E; Clinical Laboratory, Department of Clinical Diagnostics and Services, and Center for Clinical Studies, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland., Meli ML; Clinical Laboratory, Department of Clinical Diagnostics and Services, and Center for Clinical Studies, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland., Bönzli E; Clinical Laboratory, Department of Clinical Diagnostics and Services, and Center for Clinical Studies, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland., Meili T; Clinical Laboratory, Department of Clinical Diagnostics and Services, and Center for Clinical Studies, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland., Hüttl J; Clinical Laboratory, Department of Clinical Diagnostics and Services, and Center for Clinical Studies, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland., Hatt JM; Clinic for Zoo Animals, Exotic Pets and Wildlife, Department of Small Animals, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland., Hindenlang Clerc K; Foundation Wildnispark Zurich, Alte Sihltalstrasse 38, 8135 Sihlwald, Switzerland., Kipar A; Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 268, 8057 Zurich, Switzerland., Wyss F; Zoologischer Garten Basel AG, Binningerstrasse 40, 4054 Basel, Switzerland., Wenker C; Zoologischer Garten Basel AG, Binningerstrasse 40, 4054 Basel, Switzerland., Ryser-Degiorgis MP; Institute for Fish and Wildlife Health, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland., Valenzuela Agüí C; Department of Biosystems Science and Engineering, ETH Zurich, Schanzenstrasse 44, Postfach, 4009 Basel, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Urban C; Functional Genomics Center, ETH Zurich and University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland., Beisel C; Department of Biosystems Science and Engineering, ETH Zurich, Schanzenstrasse 44, Postfach, 4009 Basel, Switzerland., Stadler T; Department of Biosystems Science and Engineering, ETH Zurich, Schanzenstrasse 44, Postfach, 4009 Basel, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Hofmann-Lehmann R; Clinical Laboratory, Department of Clinical Diagnostics and Services, and Center for Clinical Studies, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland.
Jazyk: angličtina
Zdroj: Viruses [Viruses] 2024 Mar 28; Vol. 16 (4). Date of Electronic Publication: 2024 Mar 28.
DOI: 10.3390/v16040521
Abstrakt: Many different animal species are susceptible to SARS-CoV-2, including a few Canidae (domestic dog and raccoon dog). So far, only experimental evidence is available concerning SARS-CoV-2 infections in red foxes ( Vulpes vulpes ). This is the first report of SARS-CoV-2 RNA detection in a sample from a red fox. The RT-qPCR-positive fox was zoo-kept together with another fox and two bears in the Swiss Canton of Zurich. Combined material from a conjunctival and nasal swab collected for canine distemper virus diagnostics tested positive for SARS-CoV-2 RNA with Ct values of 36.9 (E gene assay) and 35.7 (RdRp gene assay). The sample was analysed for SARS-CoV-2 within a research project testing residual routine diagnostic samples from different animal species submitted between spring 2020 and December 2022 to improve knowledge on SARS-CoV-2 infections within different animal species and investigate their potential role in a One Health context. Within this project, 246 samples from 153 different animals from Swiss zoos and other wild animal species all tested SARS-CoV-2 RT-qPCR and/or serologically negative so far, except for the reported fox. The source of SARS-CoV-2 in the fox is unknown. The fox disappeared within the naturally structured enclosure, and the cadaver was not found. No further control measures were undertaken.
Databáze: MEDLINE
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