| Autor: |
Gomes CP; Bionanomanufacturing Center, Institute for Technological Research-IPT, Sao Paulo 05508-901, SP, Brazil., Martins AGC; Bionanomanufacturing Center, Institute for Technological Research-IPT, Sao Paulo 05508-901, SP, Brazil., Nunes SE; Bionanomanufacturing Center, Institute for Technological Research-IPT, Sao Paulo 05508-901, SP, Brazil., Ramos B; Microfluidic & Photoelectrocatalytic Engineering Group, Department of Chemical Engineering, FEI University Center, São Bernardo do Campo 09850-901, SP, Brazil., Wisinewski HR; Bionanomanufacturing Center, Institute for Technological Research-IPT, Sao Paulo 05508-901, SP, Brazil., Reis JLMS; Bionanomanufacturing Center, Institute for Technological Research-IPT, Sao Paulo 05508-901, SP, Brazil., Lima AP; Bionanomanufacturing Center, Institute for Technological Research-IPT, Sao Paulo 05508-901, SP, Brazil., Aoyagi TY; Bionanomanufacturing Center, Institute for Technological Research-IPT, Sao Paulo 05508-901, SP, Brazil., Goncales I; Bionanomanufacturing Center, Institute for Technological Research-IPT, Sao Paulo 05508-901, SP, Brazil., Maia DS; Bionanomanufacturing Center, Institute for Technological Research-IPT, Sao Paulo 05508-901, SP, Brazil., Tunussi AS; Bionanomanufacturing Center, Institute for Technological Research-IPT, Sao Paulo 05508-901, SP, Brazil., Menossi MS; Bionanomanufacturing Center, Institute for Technological Research-IPT, Sao Paulo 05508-901, SP, Brazil., Pereira SM Jr; Bionanomanufacturing Center, Institute for Technological Research-IPT, Sao Paulo 05508-901, SP, Brazil., Turrini PCG; Bionanomanufacturing Center, Institute for Technological Research-IPT, Sao Paulo 05508-901, SP, Brazil., Gervasio JHDB; Bionanomanufacturing Center, Institute for Technological Research-IPT, Sao Paulo 05508-901, SP, Brazil., Verona BM; Bionanomanufacturing Center, Institute for Technological Research-IPT, Sao Paulo 05508-901, SP, Brazil., Cerize NNP; Bionanomanufacturing Center, Institute for Technological Research-IPT, Sao Paulo 05508-901, SP, Brazil. |
| Abstrakt: |
DNA data storage based on synthetic oligonucleotides is a major attraction due to the possibility of storage over long periods. Nowadays, the quantity of data generated has been growing exponentially, and the storage capacity needs to keep pace with the growth caused by new technologies and globalization. Since DNA can hold a large amount of information with a high density and remains stable for hundreds of years, this technology offers a solution for current long-term data centers by reducing energy consumption and physical storage space. Currently, research institutes, technology companies, and universities are making significant efforts to meet the growing need for data storage. DNA data storage is a promising field, especially with the advancement of sequencing techniques and equipment, which now make it possible to read genomes (i.e., to retrieve the information) and process this data easily. To overcome the challenges associated with developing new technologies for DNA data storage, a message encoding and decoding exercise was conducted at a Brazilian research center. The exercise performed consisted of synthesizing oligonucleotides by the phosphoramidite route. An encoded message, using a coding scheme that adheres to DNA sequence constraints, was synthesized. After synthesis, the oligonucleotide was sequenced and decoded, and the information was fully recovered. |
