| Autor: |
Perin PP; Department of Pathology, Reproduction and One Health, São Paulo State University, Jaboticabal 14884900, Brazil., Turmina T; Department of Pathology, Reproduction and One Health, São Paulo State University, Jaboticabal 14884900, Brazil., Arias-Pacheco CA; Department of Pathology, Reproduction and One Health, São Paulo State University, Jaboticabal 14884900, Brazil., Gomes JS; Department of Pathology, Reproduction and One Health, São Paulo State University, Jaboticabal 14884900, Brazil., Andrade LO; Department of Pathology, Reproduction and One Health, São Paulo State University, Jaboticabal 14884900, Brazil., Zolla NO; Department of Pathology, Reproduction and One Health, São Paulo State University, Jaboticabal 14884900, Brazil., Mendonça TO; Department of Pathology, Reproduction and One Health, São Paulo State University, Jaboticabal 14884900, Brazil., Oliveira WJ; Department of Pathology, Reproduction and One Health, São Paulo State University, Jaboticabal 14884900, Brazil., Fahl WO; Laboratory of Rabies Diagnosis, Pasteur Institute, São Paulo 01311090, Brazil., Scheffer KC; Laboratory of Rabies Diagnosis, Pasteur Institute, São Paulo 01311090, Brazil., Cunha Neto RDS; Laboratory of Rabies Diagnosis, Pasteur Institute, São Paulo 01311090, Brazil., Chierato MER; Laboratory of Rabies Diagnosis, Pasteur Institute, São Paulo 01311090, Brazil., Mori E; Laboratory of Rabies Diagnosis, Pasteur Institute, São Paulo 01311090, Brazil., Felicio ALA; Agricultural Defense Coordination, Department of Agriculture and Supply of the State of São Paulo, Campinas 13070178, Brazil., Haga GSI; Agricultural Defense Coordination, Department of Agriculture and Supply of the State of São Paulo, Campinas 13070178, Brazil., Guido MC; Agricultural Defense Coordination, Department of Agriculture and Supply of the State of São Paulo, Campinas 13070178, Brazil., Barrochelo LH; Agricultural Defense Coordination, Department of Agriculture and Supply of the State of São Paulo, Campinas 13070178, Brazil., Marcos ADS; Agricultural Defense Coordination, Department of Agriculture and Supply of the State of São Paulo, Campinas 13070178, Brazil., Lux Hoppe EG; Department of Pathology, Reproduction and One Health, São Paulo State University, Jaboticabal 14884900, Brazil. |
| Abstrakt: |
Rabies, one of the most lethal global zoonoses, affects all mammals. It remains circulating worldwide in sylvatic cycles through terrestrial and airborne reservoirs, and in Brazil, bats are currently the main reservoirs and source of transmission. Wild boars, an important invasive alien species in Brazil, are a proven food source for hematophagous bats and may participate in the Brazilian sylvatic cycle of rabies. We evaluated the presence of this pathogen in hunted wild boars from the São Paulo state using histopathology, the direct fluorescent antibody test (DFA), viral isolation in cell culture (VICC), the rapid fluorescent focus inhibition test (RFFIT), and quantitative reverse transcription polymerase chain reaction (RT-qPCR). The results of histopathological, DFA, VICC, and RT-qPCR analysis were negative for all samples; seven serum samples tested positive in the RFFIT, and titers ranged from 0.13 IU/mL to 0.5 IU/mL. The presence of rabies virus-neutralizing antibodies in the studied wild boars suggests the circulation of the virus in these animals. Educative actions directed at hunters should include information on the prevention of this important zoonosis. |
