Exploring the Relationship between Psychoneuroimmunology and Oral Diseases: A Comprehensive Review and Analysis.

Autor:	Ganesan A; Department of Oral Medicine and Radiology, SRM Dental College, Chennai, Tamil Nadu, India., Kumar G; Department of Periodontics, Madha Dental College and Hospital, Chennai, Tamil Nadu, India., Gauthaman J; Department of Oral Medicine and Radiology, SRM Dental College, Chennai, Tamil Nadu, India., Lakshmi KC; Department of Oral Medicine and Radiology, SRM Dental College, Chennai, Tamil Nadu, India., Kumbalaparambil YA; Department of Oral Medicine and Radiology, SRM Dental College, Chennai, Tamil Nadu, India.
Jazyk:	angličtina
Zdroj:	Journal of lifestyle medicine [J Lifestyle Med] 2024 Feb 29; Vol. 14 (1), pp. 13-19.
DOI:	10.15280/jlm.2024.14.1.13
Abstrakt:	The relationship between psychoneuroimmunology (PNI) and oral health has recently garnered increasing attention due to the intricate interaction among psychological factors, the nervous system, immune responses, and oral diseases. This comprehensive review aims to elucidate the multifaceted connections between PNI and various oral conditions and conduct an in-depth analysis. Psychological factors, such as stress, anxiety, and depression, have been linked to oral microbiome alterations and immune function and the development and progression of oral diseases, such as periodontal disorders, oral ulcers, and temporomandibular disorders. Conversely, oral health conditions, particularly chronic periodontitis, have been associated with systemic inflammation, affecting mental health and overall well-being through neuroendocrine-immune pathways. Moreover, neural mechanisms, including the brain-gut axis and the autonomic nervous system, significantly influenced oral health through immune modulation and inflammatory responses. Understanding these complex interactions has implications for therapeutic interventions that target both psychological well-being and oral health outcomes. This review synthesizes current research findings from various disciplines, including immunology, neuroscience, dentistry, and psychology, to offer a comprehensive understanding of the bidirectional relationship between PNI and oral diseases. The implications of these interactions on treatment strategies, preventive measures, and interdisciplinary approaches underscore the need for integrated healthcare models that address psychological and oral health aspects to improve outcomes and quality of life in patients. Competing Interests: • Conflicts of Interest: No conflict of interest. (© 2024 Journal of Lifestyle Medicine.)
Databáze:	MEDLINE
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