Cardiovascular risk burden and disability: findings from the International Mobility in Aging Study (IMIAS).

Autor:	Martinez-Aristizábal JD; Internal Medicine, Critical Care Department, Pablo Tobón Uribe Hospital, Medellín, Colombia., Curcio CL; Research Group in Geriatrics and Gerontology, Faculty of Health Sciences, Universidad de Caldas, Manizales, Colombia., Fernandes J; Laboratory of Physical Therapy and Collective Health, Physical Therapy Department, Federal University of Pernambuco, Jornalista Aníbal Fernandes Avenue Recife, Brazil., Vafael A; Department of Public Health Sciences, Queen's University, Kingston, ON, Canada., Gomes CDS; Department of Physiotherapy, University of Pernambuco, BR 203, Km, Brazil., Gomez F; Research Group in Geriatrics and Gerontology, Faculty of Health Sciences, Universidad de Caldas, Manizales, Colombia.
Jazyk:	angličtina
Zdroj:	Journal of geriatric cardiology : JGC [J Geriatr Cardiol] 2024 Mar 28; Vol. 21 (3), pp. 331-339.
DOI:	10.26599/1671-5411.2024.03.002
Abstrakt:	Background: The association of cardiovascular risk burden with disability is unclear. We examined the association between trajectories of the Framingham general cardiovascular disease risk score (FGCRS) with the trajectories of limitations of physical function in older adults. Methods: A total of 1219 participants with no disabilities from the International Mobility in Aging Study (IMIAS) study who had up to three repeated measures of FGCRS between 2012-2016 and without a history of stroke or coronary heart disease at baseline and follow-up were included. FGCRS at baseline was assessed and categorized into tertiles. Physical function was evaluated with the Short Physical Performance Battery (SPPB). The data were analyzed using linear mixed-effects models. Results: At baseline, FGCRS ranged between 3-94 (mean score: 24 ± 15.8), participants were 32 (2.6%), 502 (41.2%) and 685 (56.2%) in lowest, middle, and highest tertiles, respectively. In the trajectories of limitations of physical function, the lowest FGCRS had no differences, while the middle and highest had a decrease in physical performance between 2012-2014 ( P = 0.0001). Age, being female, living in Andes Mountains, having middle and highest FGCRS, higher alcohol consumption, being obese, lack of exercise and cognitive impairment increase the probability of disability ( P < 0.05). Alternatively, living in more developed regions and having a higher educational level reduced the probability of disability during the follow-up time ( P < 0.05). Conclusions: Higher cardiovascular risk burden is associated with decreased physical performance, especially in gait. Results suggest SPPB may provide a measure of cardiovascular health in older adults. (© 2024 JGC All rights reserved; www.jgc301.com.)
Databáze:	MEDLINE
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