Association between early echocardiography screening of low systemic blood flow and intraventricular hemorrhage in preterm infants: a multicenter cohort study.

Autor:	Terroba-Seara S; Neonatal Intensive Care Unit, Complejo Asistencial Universitario de León, León, Spain.; Pediatric Intensive Care Unit and Pediatric Cardiology Unit, Complejo Asistencial Universitario de León, León, Spain., Oulego-Erroz I; Pediatric Intensive Care Unit and Pediatric Cardiology Unit, Complejo Asistencial Universitario de León, León, Spain. ignacio.oulego@gmail.com.; Biomedicine Institute of León, University of León, León, Spain. ignacio.oulego@gmail.com., Palanca-Arias D; Pediatric Cardiology Unit, Pediatric Intensive Care Unit, Hospital Universitario Miguel Servet, Zaragoza, Spain.; Faculty of Medicine, University of Zaragoza, Zaragoza, Spain., Galve-Pradel Z; Neonatal Intensive Care Unit, Hospital Universitario Miguel Servet, Zaragoza, Spain., Delgado-Nicolás S; Department of Pediatrics, Hospital Universitario Central de Asturias, Oviedo, Spain., Pérez-Pérez A; Department of Pediatrics, Hospital Universitario Central de Asturias, Oviedo, Spain., Rodríguez-Ozcoidi J; Neonatal Intensive Care Unit, Hospital Universitario de Navarra, Pamplona, Spain., Lavilla-Oíz A; Neonatal Intensive Care Unit, Hospital Universitario de Navarra, Pamplona, Spain., Bravo MC; Department of Neonatology, La Paz University Hospital, Madrid, Spain.; IdiPaz (Hospital La Paz Institute for Health Research), Madrid, Spain. IdiPaz (Hospital La Paz Institute for Health Research), Madrid, Spain., La Banda-Montalvo L; Department of Neonatology, La Paz University Hospital, Madrid, Spain.; IdiPaz (Hospital La Paz Institute for Health Research), Madrid, Spain. IdiPaz (Hospital La Paz Institute for Health Research), Madrid, Spain., Méndez-Abad P; Neonatal Intensive Care Unit, Hospital Universitario Puerta del Mar, Cádiz, Spain., Zafra-Rodríguez P; Neonatal Intensive Care Unit, Hospital Universitario Puerta del Mar, Cádiz, Spain., Rodeño-Fernández L; Neonatal Intensive Care Unit, Hospital Universitario de Basurto, Basurto, Spain., Montero-Gato J; Neonatal Intensive Care Unit, Hospital Universitario de Basurto, Basurto, Spain., Bustamante-Hervás C; Neonatal Intensive Care Unit, Hospital Universitario de Burgos, Burgos, Spain., Vega-Del-Val C; Neonatal Intensive Care Unit, Hospital Universitario de Burgos, Burgos, Spain., Rodríguez-Fanjul J; Pediatric and Neonatal Intensive Care Unit, Hospital Universitario German Trías I Pujol, Badalona, Spain., Mayordomo-Colunga J; Pediatric Intensive Care Unit, Hospital Central de Asturias, Oviedo, Spain.; Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain.; Centro de Investigación Biomédica en Red-Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain., Alegría-Echauri I; Neonatal Intensive Care Unit, Hospital Universitario de Navarra, Pamplona, Spain., Pérez-Álvarez A; Investigation Unit, Complejo Asistencial Universitario de León, León, Spain.; Instituto de Ciencias de la Salud de Castilla y León (ICSCYL), Soria, Spain.
Jazyk:	angličtina
Zdroj:	Journal of perinatology : official journal of the California Perinatal Association [J Perinatol] 2024 Oct; Vol. 44 (10), pp. 1496-1503. Date of Electronic Publication: 2024 Apr 25.
DOI:	10.1038/s41372-024-01968-6
Abstrakt:	Objective: To determine whether early echocardiography screening of low systemic blood flow reduces intraventricular hemorrhage in preterm infants. Study Design: Prospective multicenter study in preterm infants below 33 weeks of gestational age at nine neonatal units. Five units performed early echocardiography screening for low systemic blood flow and guided clinical management (exposure group) and 4 units did not (control group). Our main outcome was ≥grade II intraventricular hemorrhage or death within the first 7 days of life. The main analysis used the inverse probability of treatment weighting. Results: Three hundred and thirty-two preterm infants (131 in the exposure group and 201 in the control group) were included. Exposure to early echocardiography screening was associated with a significant reduction in ≥grade II intraventricular hemorrhage or early death [odds ratio 0.285 (95% CI: 0.133-0.611); p = 0.001]. Conclusions: Early echocardiography screening for low systemic blood flow may reduce the incidence of intraventricular hemorrhage in preterm infants. (© 2024. The Author(s), under exclusive licence to Springer Nature America, Inc.)
Databáze:	MEDLINE
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