Theoretical investigations on the laser isotope separation of 175 Yb for medical applications.

Autor: Sankari M; Bhabha Atomic Research Centre, Visakhapatnam, Andhra Pradesh, India., Suryanarayana MV; Bhabha Atomic Research Centre, Visakhapatnam, Andhra Pradesh, India. Electronic address: suryabarcv@gmail.com.
Jazyk: angličtina
Zdroj: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine [Appl Radiat Isot] 2024 Jul; Vol. 209, pp. 111328. Date of Electronic Publication: 2024 Apr 21.
DOI: 10.1016/j.apradiso.2024.111328
Abstrakt: The possibility of laser isotope separation of 175 Yb from irradiated natural Yb has been investigated. The optimum process parameters such as powers and bandwidths of the lasers, Doppler broadening and the number density of the atoms have been derived through density matrix calculations. It has been shown that it is possible to produce 175 Yb (>42% enriched) at a production rate of 62 μg/hour (or 1.5 mg/day). This corresponds to the production rate of 1350 patient doses (of 7.4 GBq each) per day. The radionuclidic purity of the isotopic mixture is expected to be 99.9999%. The method is highly suitable for the countries having only low-flux nuclear reactors.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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