Mesoporous Gold: Substrate-Dependent Growth Dynamics, Strain Accumulation, and Electrocatalytic Activity for Biosensing.

Autor: Park H; Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD, 4072, Australia.; School of Mechanical and Mining Engineering, Faculty of Engineering, Architecture, and Information Technology (EAIT), The University of Queensland, Brisbane, QLD, 4072, Australia., Masud MK; Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD, 4072, Australia., Ashok A; Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD, 4072, Australia., Kim M; Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD, 4072, Australia., Wahab MA; Energy and Process Engineering Laboratory, School of Mechanical, Medical and Process Engineering, Faculty of Science, Queensland University of Technology, 2 George Street, Brisbane, QLD, 4000, Australia., Zhou J; School of Information and Communication Technology, Griffith University, Brisbane, QLD, 4072, Australia., Terasawa Y; Faculty of Advanced Science and Technology, Kumamoto University, 2-39-1 Chuo-ku, Kurokami, Kumamoto-shi, Kumamoto, 860-8555, Japan., Gallo CS; Translational Extracellular Vesicles in Obstetrics and Gynae-Oncology Group and UQ Centre for Extracellular Vesicle Nanomedicine, University of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, QLD, 4029, Australia., Nguyen NT; Queensland Micro- and Nanotechnology Centre (QMNC), Griffith University, Nathan Campus, QLD, 4111, Australia., Hossain MSA; Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD, 4072, Australia.; School of Mechanical and Mining Engineering, Faculty of Engineering, Architecture, and Information Technology (EAIT), The University of Queensland, Brisbane, QLD, 4072, Australia., Yamauchi Y; Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD, 4072, Australia.; Department of Materials Process Engineering Graduate School of Engineering, Nagoya University, Nagoya, 464-8603, Japan.; Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul, 03722, South Korea., Kaneti YV; Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD, 4072, Australia.
Jazyk: angličtina
Zdroj: Small (Weinheim an der Bergstrasse, Germany) [Small] 2024 Aug; Vol. 20 (35), pp. e2311645. Date of Electronic Publication: 2024 Apr 24.
DOI: 10.1002/smll.202311645
Abstrakt: Understanding the growth of mesoporous crystalline materials, such as mesoporous metals, on different substrates can provide valuable insights into the crystal growth dynamics and the redox reactions that influence their electrochemical sensing performance. Herein, it is demonstrated how the amorphous nature of the glass substrate can suppress the typical <111> oriented growth in mesoporous Au (mAu) films. The suppressed <111> growth is manifested as an accumulation of strain, leading to the generation of abundant surface defects, which are beneficial for enhancing the electrochemical activity. The fine structuring attained enables dramatically accelerated diffusion and enhances the electrochemical sensing performance for disease-specific biomolecules. As a proof-of-concept, the as-fabricated glass-grown mAu film demonstrates high sensitivity in electrochemical detection of SARS-CoV-2-specific RNA with a limit of detection (LoD) as low as 1 attomolar (aM).
(© 2024 The Authors. Small published by Wiley‐VCH GmbH.)
Databáze: MEDLINE
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