Inhibition of autophagy antagonizes breast cancer brain metastogenesis and augments the anticancer activity of lapatinib.

Autor: Nawrocki ST; Department of Medicine, Division of Hematology and Oncology, University of Arizona Cancer Center, Tucson, Arizona, USA.; Department of Urology, University of Arizona, Tucson, Arizona, USA., Espitia CM; Department of Medicine, Division of Hematology and Oncology, University of Arizona Cancer Center, Tucson, Arizona, USA., Espinoza MJC; Department of Medicine, Division of Hematology and Oncology, University of Arizona Cancer Center, Tucson, Arizona, USA., Jones TM; Department of Medicine, Division of Hematology and Oncology, University of Arizona Cancer Center, Tucson, Arizona, USA., Gamble ME; Department of Medicine, Division of Hematology and Oncology, University of Arizona Cancer Center, Tucson, Arizona, USA., Sureshkumar S; Department of Medicine, Division of Hematology and Oncology, University of Arizona Cancer Center, Tucson, Arizona, USA., Chang M; Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona, USA., Wang W; Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona, USA.; Department of Pharmacology and Toxicology, University of Arizona, Tucson, Arizona, USA.; Arizona Center for Drug Discovery, University of Arizona, Tucson, Arizona, USA., Carew JS; Department of Medicine, Division of Hematology and Oncology, University of Arizona Cancer Center, Tucson, Arizona, USA.
Jazyk: angličtina
Zdroj: Clinical and translational medicine [Clin Transl Med] 2024 Apr; Vol. 14 (4), pp. e1662.
DOI: 10.1002/ctm2.1662
Databáze: MEDLINE
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