Factors influencing the positivity of diagnostic tests for congenital syphilis.

Autor:	Ribeiro RS; Faculty of Medicine of São José do Rio Preto - São José do Rio Preto (SP), Brazil., Sasaki NSGMDS; Faculty of Medicine of São José do Rio Preto - São José do Rio Preto (SP), Brazil., Queiroz AMA; Faculty of Medicine of São José do Rio Preto - São José do Rio Preto (SP), Brazil., Ferreira ACM; Union of Colleges of Great Lakes - São José do Rio Preto (SP), Brazil., Segura GS; Faculty of Medicine of São José do Rio Preto - São José do Rio Preto (SP), Brazil., Santos MLSG; Faculty of Medicine of São José do Rio Preto - São José do Rio Preto (SP), Brazil., Souza LH; Faculty of Medicine of São José do Rio Preto - São José do Rio Preto (SP), Brazil., Lourenção LG; Universidade Federal do Rio Grande - Rio Grande (RS), Brazil.
Jazyk:	angličtina
Zdroj:	Revista da Associacao Medica Brasileira (1992) [Rev Assoc Med Bras (1992)] 2024 Apr 22; Vol. 70 (5), pp. e20231006. Date of Electronic Publication: 2024 Apr 22 (Print Publication: 2024).
DOI:	10.1590/1806-9282.20231006
Abstrakt:	Objective: The objective of this study was to analyze the factors that influence the positivity of treponemal and non-treponemal tests in cases of congenital syphilis. Methods: This cross-sectional and correlational study was carried out from the analysis of the database of Disease and Notification Information System (SINAN, in Portuguese) using the data obtained through the Epidemiological Surveillance Group 29, with 639 notifications of congenital syphilis between 2007 and 2018. The data were analyzed by a descriptive and inferential analysis from logistic regression with a significance level of 5% (p≤0.05). Results: The positivity of the treponemal test was higher by 4.5 times in infants living in rural areas and 19.6 times among those whose mothers obtained the diagnosis of syphilis after birth. The treponemal test showed positivity 3.2 times higher for the variable "having been diagnosed between 2007 and 2015" and 5.5 times higher for the variable "having been diagnosed with maternal syphilis in the postpartum period." Conclusion: This study shows that testing during prenatal care is essential for early diagnosis and prevention of syphilis complications.
Databáze:	MEDLINE
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