Bilateral acute depigmentation of the iris (BADI) and bilateral acute iris transillumination (BAIT): A case series from a center in Brazil.

Autor: Costa FV; Laboratory of Infectious Diseases in Ophthalmology, Instituto Nacional de Infectologia, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil., Silva AGE; Laboratory of Infectious Diseases in Ophthalmology, Instituto Nacional de Infectologia, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil., Pedroso LA; Laboratory of Infectious Diseases in Ophthalmology, Instituto Nacional de Infectologia, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil., Biancardi AL; Laboratory of Infectious Diseases in Ophthalmology, Instituto Nacional de Infectologia, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil., Curi ALL; Laboratory of Infectious Diseases in Ophthalmology, Instituto Nacional de Infectologia, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.
Jazyk: angličtina
Zdroj: Arquivos brasileiros de oftalmologia [Arq Bras Oftalmol] 2024 Apr 19; Vol. 87 (4), pp. e2023. Date of Electronic Publication: 2024 Apr 19 (Print Publication: 2024).
DOI: 10.5935/0004-2749.2023-0219
Abstrakt: Bilateral acute depigmentation of the iris and bilateral acute iris transillumination (BAIT) are similar clinical entities. The former causes acute-onset depigmentation of the iris stroma without transillumination, whereas the latter causes depigmentation of the iris pigment epithelium with transillumination. The etiopathogenesis of these conditions is not yet fully understood, but the proposed causes include the use of systemic antibiotics (especially moxifloxacin) and viral triggers. We present a case series of five female patients with a mean age of 41 (32-45) years, all of whom suffered acute onset of bilateral pain and redness of the eyes after moxifloxacin use (oral or topical). It is important for ophthalmologists to be aware of the two forms of iris depigmentation since this case series suggests that SARS-CoV-2 or its empirical treatment with moxifloxacin may trigger iris depigmentation. If this is the case, clinicians will likely see increased incidences of bilateral acute depigmentation of the iris and bilateral acute iris transillumination during and after the COVID-19 pandemic.
Databáze: MEDLINE
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