Landmarks in the history of neurosyphilis: the neglected observations of Vincenzo Chiarugi.
| Autor: | Di Francesco D; Sussex Partnership NHS Foundation Trust, UK. |
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| Jazyk: | angličtina |
| Zdroj: | History of psychiatry [Hist Psychiatry] 2024 Sep; Vol. 35 (3-4), pp. 334-340. Date of Electronic Publication: 2024 Apr 23. |
| DOI: | 10.1177/0957154X241247959 |
| Abstrakt: | After the emergence of syphilis in Europe in 1495, it would take over 400 years to unpick the full course of the infection, including the involvement of the brain and spinal cord. This syndrome of mental and physical deterioration was called 'general paralysis of the insane' (GPI). Traditionally, the earliest clear description of GPI is attributed to Haslam in 1798. However, here I describe three clear cases and three highly suggestive cases, together with autopsy findings, published in 1794 by the Italian psychiatrist Vincenzo Chiarugi. Historically, Chiarugi's scholarship has been neglected in favour of English- and French-speaking physicians. His observations also give a rare clue regarding the prevalence of syphilis, suggesting a foothold in northern Italy in the late eighteenth century. Competing Interests: Declaration of conflicting interestsThe author declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. |
| Databáze: | MEDLINE |
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