Febrile Seizures: A Systematic Review of Different Guidelines.

Autor: Corsello A; Department of Clinical Science and Community Health, University of Milan, Milan, Italy., Marangoni MB; Department of Clinical Science and Community Health, University of Milan, Milan, Italy., Macchi M; Department of Clinical Science and Community Health, University of Milan, Milan, Italy., Cozzi L; Department of Clinical Science and Community Health, University of Milan, Milan, Italy; Struttura Complessa Pediatria, Presidio Ospedaliero Magenta, ASST Ovest Milanese, Milan, Italy., Agostoni C; Department of Clinical Science and Community Health, University of Milan, Milan, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Pediatric Unit, Milan, Italy., Milani GP; Department of Clinical Science and Community Health, University of Milan, Milan, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Pediatric Unit, Milan, Italy., Dilena R; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Neuropathophysiology Unit, Milan, Italy. Electronic address: robertino.dilena@policlinico.mi.it.
Jazyk: angličtina
Zdroj: Pediatric neurology [Pediatr Neurol] 2024 Jun; Vol. 155, pp. 141-148. Date of Electronic Publication: 2024 Apr 03.
DOI: 10.1016/j.pediatrneurol.2024.03.024
Abstrakt: Background: Febrile seizures (FS) are the most common neurological disorder in pediatric age. FS affect 2% to 12% of children and result from a complex interplay of genetic and environmental factors. Effective management and unambiguous recommendations are crucial for allocating health care resources efficiently and ensuring cost-effectiveness in treating FS.
Methods: This systematic review compares existing guidelines to provide insights into FS management. Seven guidelines published between 1991 and 2021, from Japan, United Kingdom, United States, Mexico, India, and Italy, were included. Data extraction covered definitions, diagnostic criteria, hospital admission criteria, diagnostic tests, management, and prophylaxis recommendations.
Results: Hospital admission criteria varied but typically included age <18 months and complex FS. Neuroimaging and lumbar puncture recommendations varied, with most guidelines suggesting limited use. Pharmacologic prophylaxis was generally discouraged for simple FS but considered only for high-risk cases, due to the benign nature of FS and the potential side effects of antiseizure medications.
Conclusions: Guidelines on FS exhibit similarities and differences, highlighting the need for standardized management and improved parental education to enhance clinical outcomes and reduce economic and social costs associated with FS. Future research should focus on creating updated international guidelines and ensuring their practical implementation.
Competing Interests: Declaration of competing interest None to declare.
(Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: