Undernourished Household Contacts Are at Increased Risk of Tuberculosis (TB) Disease, but not TB Infection-a Multicenter Prospective Cohort Analysis.

Autor: Sinha P; Department of Medicine, Section of Infectious Diseases, Boston Medical Center, Boston, Massachusetts, USA.; Section of Infectious Diseases, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Ezhumalai K; Department of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India., Du X; Section of Infectious Diseases, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Ponnuraja C; Indian Council of Medical Research, National Institute for Research in Tuberculosis, Chennai, Tamil Nadu, India., Dauphinais MR; Section of Infectious Diseases, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Gupte N; Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals-Johns Hopkins University Clinical Research Site, Pune, Maharashtra, India.; Center for Infectious Diseases in India, Johns Hopkins India, Pune, Maharashtra, India., Sarkar S; Department of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India., Gupta A; Division of Infectious Diseases, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA., Gaikwad S; Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, BJMC Clinical Research Site, Pune, Maharashtra, India., Thangakunam B; Department of Pulmonary Medicine, Christian Medical College, Vellore, Tamil Nadu, India., Paradkar M; Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals-Johns Hopkins University Clinical Research Site, Pune, Maharashtra, India.; Center for Infectious Diseases in India, Johns Hopkins India, Pune, Maharashtra, India., Christopher DJ; Department of Pulmonary Medicine, Christian Medical College, Vellore, Tamil Nadu, India., Mave V; Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals-Johns Hopkins University Clinical Research Site, Pune, Maharashtra, India.; Center for Infectious Diseases in India, Johns Hopkins India, Pune, Maharashtra, India.; Division of Infectious Diseases, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA., Viswanathan V; Prof. M. Viswanathan Diabetes Research Centre, Chennai, Tamil Nadu, India., Ellner JJ; Center for Emerging Pathogens, Department of Medicine, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Newark, New Jersey, USA., Kornfeld H; Department of Medicine, UMass Chan Medical School, Worcester, Massachusetts, USA., Horsburgh CR Jr; Section of Infectious Diseases, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA.; Department of Global Health, Boston University School of Public Health, Boston, Massachusetts, USA., Padmapriyadarsini C; Indian Council of Medical Research, National Institute for Research in Tuberculosis, Chennai, Tamil Nadu, India., Gupte A; Department of Global Health, Boston University School of Public Health, Boston, Massachusetts, USA.
Jazyk: angličtina
Zdroj: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2024 Jul 19; Vol. 79 (1), pp. 233-236.
DOI: 10.1093/cid/ciae149
Abstrakt: Undernutrition is the leading risk factor for tuberculosis (TB) globally and in India. This multicenter prospective cohort analysis from India suggests that undernutrition is associated with increased risk of TB disease but not TB infection among household contacts of persons with TB.
Competing Interests: Potential conflicts of interest. The authors: No reported conflicts of interest. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.
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Databáze: MEDLINE