Biochemical and biophysical interaction of rare earth elements with biomacromolecules: A comprehensive review.

Autor: Samal RR; Biochemistry & Biophysics Laboratory, Environment & Sustainability Department, CSIR-Institute of Minerals and Materials Technology, Bhubaneswar, 751013, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India., Subudhi U; Biochemistry & Biophysics Laboratory, Environment & Sustainability Department, CSIR-Institute of Minerals and Materials Technology, Bhubaneswar, 751013, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. Electronic address: usubudhi@immt.res.in.
Jazyk: angličtina
Zdroj: Chemosphere [Chemosphere] 2024 Jun; Vol. 357, pp. 142090. Date of Electronic Publication: 2024 Apr 20.
DOI: 10.1016/j.chemosphere.2024.142090
Abstrakt: The growing utilization of rare earth elements (REEs) in industrial and technological applications has captured global interest, leading to the development of high-performance technologies in medical diagnosis, agriculture, and other electronic industries. This accelerated utilization has also raised human exposure levels, resulting in both favourable and unfavourable impacts. However, the effects of REEs are dependent on their concentration and molecular species. Therefore, scientific interest has increased in investigating the molecular interactions of REEs with biomolecules. In this current review, particular attention was paid to the molecular mechanism of interactions of Lanthanum (La), Cerium (Ce), and Gadolinium (Gd) with biomolecules, and the biological consequences were broadly interpreted. The review involved gathering and evaluating a vast scientific collection which primarily focused on the impact associated with REEs, ranging from earlier reports to recent discoveries, including studies in human and animal models. Thus, understanding the molecular interactions of each element with biomolecules will be highly beneficial in elucidating the consequences of REEs accumulation in the living organisms.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: