Malignant syphilis requiring differentiation from Kaposi's sarcoma.

Autor:	Tokano M; Department of Infectious Disease and Infection Control, Saitama Medical University, 38 Morohongo, Moroyama, Saitama 350-0495, Japan.; Department of Allergy and Immunology, Faculty of Medicine, Saitama Medical University, 38 Morohongo, Moroyama, Saitama 350-0495, Japan., Tarumoto N; Department of Infectious Disease and Infection Control, Saitama Medical University, 38 Morohongo, Moroyama, Saitama 350-0495, Japan., Imai K; Department of Infectious Disease and Infection Control, Saitama Medical University, 38 Morohongo, Moroyama, Saitama 350-0495, Japan., Yamaguchi H; Department of Pathology, Faculty of Medicine, Saitama Medical University, 38 Morohongo, Moroyama, Saitama 350-0495, Japan., Takeji M; Department of Dermatology, Saitama Medical University, 38 Morohongo, Moroyama, Saitama 350-0495, Japan., Inayoshi F; Department of Rheumatology and Applied Immunology, Saitama Medical University, 38 Morohongo, Moroyama, Saitama 350-0495, Japan., Okamoto K; Department of Rheumatology and Applied Immunology, Saitama Medical University, 38 Morohongo, Moroyama, Saitama 350-0495, Japan., Okumura N; Department of Rheumatology and Applied Immunology, Saitama Medical University, 38 Morohongo, Moroyama, Saitama 350-0495, Japan., Maesaki S; Department of Infectious Disease and Infection Control, Saitama Medical University, 38 Morohongo, Moroyama, Saitama 350-0495, Japan.
Jazyk:	angličtina
Zdroj:	IDCases [IDCases] 2024 Apr 16; Vol. 36, pp. e01943. Date of Electronic Publication: 2024 Apr 16 (Print Publication: 2024).
DOI:	10.1016/j.idcr.2024.e01943
Abstrakt:	Malignant syphilis (MS) is a rare variant of secondary syphilis. Also known as rupioid syphilis, MS is characterized by the presence of multiple papules, papulopustules, black lamellate crust that may resemble an oyster shell, or nodules with ulceration lacking central clearing. MS is often associated with immunodeficiency and frequently co-occurs with HIV infection. We here report a case of MS in a patient with HIV infection. HIV infection can cause atypical clinical symptoms of syphilis. In this case, unlike previous cases, cutaneous lesions of MS were limited to the face, making the diagnosis challenging based on clinical findings alone. However, his laboratory findings, appearance of the Jarisch-Herxheimer reaction, and a dramatic response to antibiotic therapy are characteristic of MS, making the diagnosis even more certain. Our case suggests the importance of physicians considering the possibility of MS when observing black-crusted lesions. Competing Interests: The authors have no conflicts of interest in association with the present study. (© 2024 The Authors.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu