A review of the topical management of acne and its associated sequelae in the Asia-Pacific region with a spotlight on trifarotene.

Autor: See JA; Central Sydney Dermatology, Sydney, NSW, Australia., Chavda R; Galderma SA, Lausanne, Switzerland., Kon KM; Galderma ANZ, North Sydney, NSW, Australia., Goodman GJ; Monash University, Clayton, VIC, Australia., Oblepias MS; AcneCure Center, Parañaque, Philippines.; Medical Center Parañaque, Parañaque, Philippines., Nadela RE; Fatima University Medical Center, Antipolo City, Philippines.; The Holistic Dermatology Clinic, Quezon City, Philippines., Oon HH; Division of Dermatology, National Skin Centre, Singapore, Singapore., Aurangabadkar S; Skin & Laser Clinic, Hyderabad, India.; New Skin Clinic, Hyderabad, India., Suh DH; Seoul National University College of Medicine, Seoul, South Korea., Chan HHL; Division of Dermatology, Department of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.; Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Lahiri K; Apollo Multispeciality Hospitals, Kolkata, India.; Wizderm Speciality Skin and Hair Clinic, Kolkata, India.
Jazyk: angličtina
Zdroj: International journal of dermatology [Int J Dermatol] 2024 Jun; Vol. 63 (6), pp. 704-713. Date of Electronic Publication: 2024 Apr 21.
DOI: 10.1111/ijd.17141
Abstrakt: Acne, a highly prevalent skin disease, can be particularly bothersome for patients of Asian background because of its impact on self-confidence and social interactions. In addition to active acne lesions, some patients may develop sequelae such as scarring, macular/postinflammatory hyperpigmentation, or erythema. The tendency of Asian skin to develop sequelae because of its increased susceptibility to irritation, cultural preferences for lighter skin phototypes, and differences in skincare regimens may all contribute to the increased burden of acne. Moreover, many Asia-Pacific countries do not have their own guidelines for acne management, and those that do often have no schedule in place for regular updates. In this article, we provide a critical review of the published guidance for the management of acne and its sequelae in the Asia-Pacific region, identifying gaps in current recommendations that could be addressed to enhance standards of acne care in Asia-Pacific countries. Along with highlighting the importance of a comprehensive skincare regimen to increase treatment efficacy and adherence, we discuss topical retinoids and retinoid combination options in the acne armamentarium that may be beneficial for sequelae prevention and management, such as adapalene 0.3% ± benzoyl peroxide 2.5%, tretinoin 0.05%, tazarotene 0.1%, and trifarotene 0.005%. In particular, trifarotene 0.005% has been observed to significantly reduce acne scar counts in a Phase 4 study. The recent data highlight the need to establish up-to-date guidance for acne and acne sequelae management in Asia-Pacific countries to provide optimal care to Asian patients.
(© 2024 Galderma and The Authors. International Journal of Dermatology published by Wiley Periodicals LLC on behalf of the International Society of Dermatology.)
Databáze: MEDLINE
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