Early diagnosis of tuberculous peritonitis in peritoneal dialysis patients using the T-SPOT test.

Autor: Okubo N; Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital Kajigaya, 1-3-1, Kajigaya, Takatsu, Kawasaki, Kanagawa, 213-8587, Japan. onaoto28@gmail.com., Suwabe T; Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital Kajigaya, 1-3-1, Kajigaya, Takatsu, Kawasaki, Kanagawa, 213-8587, Japan., Yamanouchi M; Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital Kajigaya, 1-3-1, Kajigaya, Takatsu, Kawasaki, Kanagawa, 213-8587, Japan., Ikuma D; Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital Kajigaya, 1-3-1, Kajigaya, Takatsu, Kawasaki, Kanagawa, 213-8587, Japan., Mizuno H; Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital Kajigaya, 1-3-1, Kajigaya, Takatsu, Kawasaki, Kanagawa, 213-8587, Japan., Oba Y; Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital Kajigaya, 1-3-1, Kajigaya, Takatsu, Kawasaki, Kanagawa, 213-8587, Japan., Miki K; Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital Kajigaya, 1-3-1, Kajigaya, Takatsu, Kawasaki, Kanagawa, 213-8587, Japan., Yokoyama T; Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital Kajigaya, 1-3-1, Kajigaya, Takatsu, Kawasaki, Kanagawa, 213-8587, Japan., Ishii Y; Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital Kajigaya, 1-3-1, Kajigaya, Takatsu, Kawasaki, Kanagawa, 213-8587, Japan., Sawa N; Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital Kajigaya, 1-3-1, Kajigaya, Takatsu, Kawasaki, Kanagawa, 213-8587, Japan., Nakamura Y; Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital Kajigaya, 1-3-1, Kajigaya, Takatsu, Kawasaki, Kanagawa, 213-8587, Japan., Takaya H; Department of Respiratory Medicine, Toranomon Hospital Kajigaya, Kawasaki, Kanagawa, Japan., Ubara Y; Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital Kajigaya, 1-3-1, Kajigaya, Takatsu, Kawasaki, Kanagawa, 213-8587, Japan. ubara@toranomon.gr.jp.
Jazyk: angličtina
Zdroj: CEN case reports [CEN Case Rep] 2024 Dec; Vol. 13 (6), pp. 499-503. Date of Electronic Publication: 2024 Apr 21.
DOI: 10.1007/s13730-024-00882-2
Abstrakt: A 49-year-old man was admitted with peritonitis nine months after starting continuous ambulatory peritoneal dialysis (CAPD) for kidney failure. Ceftazidime and cefazolin were started. Peritoneal dialysate culture was negative for bacteria, but antibiotic treatment was continued because peritonitis improved. Twenty days later, the patient was discharged with no signs of peritonitis. However, 40-day culture of the original peritoneal dialysate detected Mycobacterium tuberculosis, and peritonitis recurred, leading to readmission. A T-SPOT test was performed and was positive in 4 days. Anti-tuberculosis therapy was started, which cured the peritonitis. The T-SPOT test may enable early diagnosis of tuberculosis.
Competing Interests: Declarations. Conflict of interest: The authors have declared that no Conflict of interest exists. Ethics approval: The present report was produced in conformity with the Declaration of Helsinki, and the patient gave his written consent for this case report to be published.
(© 2024. The Author(s), under exclusive licence to Japanese Society of Nephrology.)
Databáze: MEDLINE
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