Male reproductive function before and after the adjustment of the COVID-19 prevention policy: a multicenter study in China.

Autor:	Li JZ; Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250000, China., Wu H; Institute of Women, Children and Reproductive Health, Shandong University, Jinan 250012, China., Wang L; Institute of Women, Children and Reproductive Health, Shandong University, Jinan 250012, China., Wang YS; Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250000, China., Kong F; Engineering Laboratory of Urinary Organ and Functional Reconstruction of Shandong Province, Jinan 250000, China., Cao LQ; The First People's Hospital of Jining, Jining 272000, China., Liang M; Department of Reproductive Medicine, The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250000, China., Wang X; Reproductive Medicine Center, Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai 264000, China., Yuan MZ; Institute of Women, Children and Reproductive Health, Shandong University, Jinan 250012, China.
Jazyk:	angličtina
Zdroj:	Asian journal of andrology [Asian J Androl] 2024 May 01; Vol. 26 (3), pp. 308-314. Date of Electronic Publication: 2024 Apr 19.
DOI:	10.4103/aja202388
Abstrakt:	At the end of 2022, the adjustment of the coronavirus disease 2019 (COVID-19) pandemic control policy in China resulted in a large-scale increase in public infection. To compare the fertility parameters of male patients before and after the adjustments of the COVID-19 pandemic control policy in China, we collected data on patients' medical histories and laboratory examinations on their first visits between June 2022 and March 2023 in five different hospitals. Data were divided into five groups according to the timeline of the policy adjustment. The data we collected from male patients included semen quality and serum reproductive hormone levels, and intergroup comparisons were made using the Mann-Whitney U and Chi-square tests. In total, 16 784 cases underwent regular semen analysis, 11 180 had sperm morphology assessments, and 7200 had reproductive hormone analyses. The data showed declining trends in semen volume, sperm motility, and the progressive sperm motility rate after the policy adjustment. Subgroup comparison revealed an initial decrease and gradual recovery in progressive motility rate. Sperm morphology analysis showed increased neck and tail abnormalities after the policy adjustment. No significant change in hormone levels was observed. Following the adjustment of the COVID-19 prevention policy in China, a decline in sperm motility and morphology was observed. This trend may gradually recover over 2 months. After the policy adjustment, reproductive hormone levels were relatively stable throughout, except for an increase in luteinizing hormone (LH). These changes in semen parameters suggest that the policy adjustment had a short- to medium-term impact on male reproductive function. (Copyright © 2024 Copyright: © The Author(s)(2024).)
Databáze:	MEDLINE
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