| Autor: |
Greičius P; National Public Health Surveillance Laboratory (NVSPL), Vilnius, Lithuania., Linkevicius M; European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden., Razmuk J; National Public Health Surveillance Laboratory (NVSPL), Vilnius, Lithuania., Sinotova J; National Public Health Surveillance Laboratory (NVSPL), Vilnius, Lithuania., Alm E; European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden., Svartström O; European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden., Bortolaia V; Statens Serum Institut (SSI), Copenhagen, Denmark., Kudirkienė E; Statens Serum Institut (SSI), Copenhagen, Denmark., Roer L; Statens Serum Institut (SSI), Copenhagen, Denmark., Hendriksen RS; Technical University of Denmark, National Food Institute (DTU Food), Kongens Lyngby, Denmark., Tamoliūnaitė G; National Public Health Surveillance Laboratory (NVSPL), Vilnius, Lithuania., Palm D; European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden., Monnet DL; European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden., Kohlenberg A; European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden., Griškevičius A; National Public Health Surveillance Laboratory (NVSPL), Vilnius, Lithuania. |
| Abstrakt: |
In 2023, an increase of OXA-48-producing Klebsiella pneumoniae was noticed by the Lithuanian National Public Health Surveillance Laboratory. Whole genome sequencing (WGS) of 106 OXA-48-producing K. pneumoniae isolates revealed three distinct clusters of carbapenemase-producing K. pneumoniae high-risk clones, including sequence type (ST) 45 (n = 35 isolates), ST392 (n = 32) and ST395 (n = 28), involving six, six and nine hospitals in different regions, respectively. These results enabled targeted investigation and control, and underscore the value of national WGS-based surveillance for antimicrobial resistance. |
