Cherubism Unmasked: A Case Report of Clinical and Histopathological Presentation.

Autor:	Akolkar S; Oral Pathology and Microbiology, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education & Research, Wardha, IND., Hande A; Oral Pathology and Microbiology, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education & Research, Wardha, IND., Sonone AM; Oral Pathology and Microbiology, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education & Research, Wardha, IND., Chavhan A; Oral Pathology and Microbiology, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education & Research, Wardha, IND., Tehzeeb H; Oral Pathology and Microbiology, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education & Research, Wardha, IND.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Mar 19; Vol. 16 (3), pp. e56456. Date of Electronic Publication: 2024 Mar 19 (Print Publication: 2024).
DOI:	10.7759/cureus.56456
Abstrakt:	Cherubism, an uncommon genetic disorder, manifests as painless swelling in both jaws. A 20-year-old male presented with symmetrical swelling in both the mandible and maxilla. The jaws exhibited bilateral expansion, typical of this condition. Dentofacial abnormalities associated with cherubism stem from mutations in the SH3BP2 gene, which plays a crucial role in regulating osteoblasts and osteoclasts. In summary, cherubism is a genetic disorder characterized by non-cancerous jaw bone lesions. Surgical intervention may be necessary for functional or aesthetic concerns. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2024, Akolkar et al.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu