Assessment of tear film parameters post-treatment with commercial eyelid cleaning wipes: a pilot study.

Autor:	Aldarwesh A; Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia., Almustanyir A; Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia., Fagehi R; Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia., Alruways K; Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia., Bin Turki A; Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia., Alghamdi M; Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia., Alanazi MK; Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia., Alabdulkader B; Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia., Alotaibi W; Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia., Alhassan M; Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia.
Jazyk:	angličtina
Zdroj:	International journal of ophthalmology [Int J Ophthalmol] 2024 Apr 18; Vol. 17 (4), pp. 659-664. Date of Electronic Publication: 2024 Apr 18 (Print Publication: 2024).
DOI:	10.18240/ijo.2024.04.08
Abstrakt:	Aim: To investigate the short-term effects of commercially available eyelid-cleaning wipes on film parameters. Methods: This study enrolled 48 healthy participants aged 20-35y (both males and females). Clinical assessment included the Ocular Surface Disease Index (OSDI) questionnaire, non-invasive tear break-up time (NITBUT), tear meniscus height (TMH), and lipid layer pattern (LLP). Based on these initial results, participants were categorized as either non-dry eye or dry eye. Participants in each group were randomly allocated to either Blephaclean ® or Systane ® treatments. Changes in NITBUT, TMH, and LLP levels before and after lid wipe treatment were assessed. Results: The dry eye group exhibited significantly higher OSDI scores and lower NITBUT and TMH levels than in the non-dry eye group ( P <0.001). Following the application of eyelid wipes (Systane ® wipes), dry eye subjects experienced a significant improvement in NITBUT levels ( P =0.0014) compared to the non-dry eye individuals. Although the remaining participants showed a marginal increase in TMH and NITBUT levels, these changes did not achieve statistical significance ( P >0.05). Similarly, the LLP levels were significantly improved with Systane ® ( P <0.001) post-treatment compared to individuals in the non-dry eye group. However, the dry eye subjects showed higher post-treatment LLP levels than the untreated group ( P <0.02). Conclusion: The short-term effects of Systane ® eyelid wipes on tear film parameters suggest their effectiveness in dry eye disease. Nonetheless, further exploration of their long-term impact is essential to justify their cost effectiveness and efficacy in treating both aqueous deficiency and evaporative dryness. Competing Interests: Conflicts of Interest: Aldarwesh A, None; Almustanyir A, None; Fagehi R, None; Alruways K, None; Bin Turki A, None; Alghamdi M, None; Alanazi MK, None; Alabdulkader B, None; Alotaibi W, None; Alhassan M, None. (International Journal of Ophthalmology Press.)
Databáze:	MEDLINE
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