An outbreak of COVID-19 after a pilgrimage to Medjugorje due to Delta sub-lineages.

Autor:	Lo Presti A; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Rubino S; Department of Biomedical Sciences, University of Sassari, Sassari, Italy., Ibba G; Department of Biomedical Sciences, University of Sassari, Sassari, Italy., Ambrosio L; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Di Martino A; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Ferraro F; Ministry of Health, Directorate-General for Health Prevention, Rome, Italy., Rapiti A; Ministry of Health, Directorate-General for Health Prevention, Rome, Italy., Maraglino F; Ministry of Health, Directorate-General for Health Prevention, Rome, Italy., Frisicale EM; Ministry of Health, Directorate-General for Health Prevention, Rome, Italy., Rezza G; Ministry of Health, Directorate-General for Health Prevention, Rome, Italy., Angioj F; Microbiology and Virology Unit, Azienda Ospedaliera Universitaria, Sassari, Italy., Uzzau S; Department of Biomedical Sciences, University of Sassari, Sassari, Italy., Contini ML; Servizio igiene e sanità pubblica, Azienda Ospedaliera Universitaria, Sassari, Italy., Manca S; Servizio igiene e sanità pubblica, Azienda Ospedaliera Universitaria, Sassari, Italy., Coghe F; Laboratorio Analisi Chimico Cliniche e Microbiologia, Azienda Ospedaliera Universitaria di Cagliari, Cagliari, Italy., Orrù G; Molecular Biology, Department of Surgical Sciences, University of Cagliari, Cagliari, Italy., Palamara AT; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Stefanelli P; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Jazyk:	angličtina
Zdroj:	Journal of infection in developing countries [J Infect Dev Ctries] 2024 Mar 31; Vol. 18 (3), pp. 332-336. Date of Electronic Publication: 2024 Mar 31.
DOI:	10.3855/jidc.18652
Abstrakt:	Introduction: A COVID-19 outbreak occurred at the end of October 2021 among pilgrims returning from Medjugorje (Bosnia and Herzegovina). Methodology: Whole genome sequencing (WGS) of SARS-CoV-2, epidemiological data, and phylogenetic analysis were used to reconstruct outbreak dynamics. Results: The results suggest that only in one case, associated with the SARS-CoV-2 sub-lineage AY.9.2, it is possible to trace back the place of contagion to Medjugorje, while the other cases were likely to be acquired in the country of origin. Conclusions: The combined use of phylogenetic data derived from WGS, and epidemiological data allowed us to study epidemic dynamics and to formulate a possible hypothesis on the place of exposure to SARS-CoV-2. The identification of different sub-lineages of the SARS-CoV-2 Delta variant also suggested that different chains of transmission contributed to the outbreak. Competing Interests: No Conflict of Interest is declared (Copyright (c) 2024 Alessandra Lo Presti, Salvatore Rubino, Gabriele Ibba, Luigina Ambrosio, Angela Di Martino, Federica Ferraro, Alessia Rapiti, Francesco Maraglino, Emanuela Maria Frisicale, Giovanni Rezza, Flavia Angioj, Sergio Uzzau, Maria Luciana Contini, Stefania Manca, Ferdinando Coghe, Germano Orrù, Anna Teresa Palamara, Paola Stefanelli, the AOUSS COVID team.)
Databáze:	MEDLINE
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